More than addiction—The nucleus accumbens contribution to development of mental disorders and neurodegenerative diseases

M Bayassi-Jakowicka, G Lietzau, E Czuba… - International journal of …, 2022 - mdpi.com
Stress and negative emotions evoked by social relationships and working conditions,
frequently accompanied by the consumption of addictive substances, and metabolic and/or …

The gut microbiota-brain axis: a new frontier on neuropsychiatric disorders

SAL Queiroz, AMM Ton, TMC Pereira… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disorder of
integrative areas of the brain, characterized by cognitive decline and disability resulting in …

Cell-type-specific afferent innervation of the nucleus accumbens core and shell

Z Li, Z Chen, G Fan, A Li, J Yuan, T Xu - Frontiers in neuroanatomy, 2018 - frontiersin.org
The nucleus accumbens (NAc) is clearly implicated in reward processing and drug
addiction, as well as in numerous neurological and psychiatric disorders; nevertheless, the …

A deep learning toolbox for automatic segmentation of subcortical limbic structures from MRI images

DN Greve, B Billot, D Cordero, A Hoopes, M Hoffmann… - Neuroimage, 2021 - Elsevier
A tool was developed to automatically segment several subcortical limbic structures
(nucleus accumbens, basal forebrain, septal nuclei, hypothalamus without mammillary …

The genetic landscape of basal ganglia and implications for common brain disorders

S Bahrami, K Nordengen, J Rokicki, AA Shadrin… - Nature …, 2024 - nature.com
The basal ganglia are subcortical brain structures involved in motor control, cognition, and
emotion regulation. We conducted univariate and multivariate genome-wide association …

Association of homocysteine-related subcortical brain atrophy with white matter lesion volume and cognition in healthy aging

H Song, PK Bharadwaj, DA Raichlen, CG Habeck… - Neurobiology of …, 2023 - Elsevier
Homocysteine (Hcy) is a vascular risk factor associated with cognitive impairment and
cerebrovascular disease but has also been implicated in Alzheimer's disease (AD). Using …

[HTML][HTML] Dose-dependent volume loss in subcortical deep grey matter structures after cranial radiotherapy

SHJ Nagtegaal, S David, MEP Philippens… - Clinical and translational …, 2021 - Elsevier
Background and purpose The relation between radiotherapy (RT) dose to the brain and
morphological changes in healthy tissue has seen recent increased interest. There already …

[HTML][HTML] Asymmetrical atrophy of thalamic subnuclei in Alzheimer's disease and amyloid-positive mild cognitive impairment is associated with key clinical features

A Low, E Mak, M Malpetti, L Chouliaras… - Alzheimer's & Dementia …, 2019 - Elsevier
Introduction Although widespread cortical asymmetries have been identified in Alzheimer's
disease (AD), thalamic asymmetries and their relevance to clinical severity in AD remain …

Brain-wide mapping of afferent inputs to accumbens nucleus core subdomains and accumbens nucleus subnuclei

L Ma, W Chen, D Yu, Y Han - Frontiers in Systems Neuroscience, 2020 - frontiersin.org
The nucleus accumbens (NAc) is the ventral part of the striatum and the interface between
cognition, emotion, and action. It is composed of three major subnuclei: ie, NAc core (NAcC) …

Predicting conversion from mild cognitive impairment to Alzheimer's disease: a multimodal approach

D Agostinho, M Simões… - Brain …, 2024 - academic.oup.com
Successively predicting whether mild cognitive impairment patients will progress to
Alzheimer's disease is of significant clinical relevance. This ability may provide information …