Brain metastases (BrMets), common for advanced-stage breast cancer patients, are
associated with poor median survival and accompanied by severe neurologic decline …

Recent advancements in spatial transcriptomics technologies have significantly enhanced
resolution and throughput, underscoring an urgent need for systematic benchmarking. To …

Intratumoral heterogeneity is intrinsically comprised of molecular alterations of tumor cells
and extrinsically from interconnections with microenvironments. This study explores the …

Phenotypic plasticity, the ability of cells to adapt their behavior in response to genetic or
environmental changes, is a fundamental biological process that drives cellular diversity in …

Background Tumour-associated macrophages (TAMs) are the most abundant immune cells
in the tumour environment and are considered to be similar to M2 macrophages, which …