Antibacterial and antioxidant activities for natural and synthetic dual-active compounds

G Martelli, D Giacomini - European Journal of Medicinal Chemistry, 2018 - Elsevier
Antimicrobial resistance is widely recognized as a grave threat to global health in the 21st
century, since the past decades have seen a dramatic increase in human-pathogenic …

[HTML][HTML] The implication of oxidative stress and AMPK-Nrf2 antioxidative signaling in pneumonia pathogenesis

W Xu, T Zhao, H Xiao - Frontiers in Endocrinology, 2020 - frontiersin.org
It is widely recognized that chemical, physical, and biological factors can singly or
synergistically evoke the excessive production of oxidative stress in pulmonary tissue that …

[HTML][HTML] In vitro and in silico evaluation of the antimicrobial and antioxidant activities of spiropyrazoline oxindole congeners

M Chalkha, K Chebbac, H Nour, A Nakkabi… - Arabian Journal of …, 2024 - Elsevier
The search for novel powerful antimicrobial and antioxidant agents is considered a dynamic
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …

Synthesis, characterization, mechanistic study, in-vitro and in-silico evaluation of antibacterial and antioxidant activities of novel pyrazole-pyrazoline hybrid systems

N Barghady, M Chalkha, I Yamari, N Aflak… - Journal of Molecular …, 2024 - Elsevier
This study describes the synthesis, characterization, and in vitro as well as in silico
assessment of the biological activity of a new series of hybrid molecules. These target …

[HTML][HTML] Arene-Ruthenium (II) complexes with carbothiamidopyrazoles as a potential alternative for antibiotic resistance in human

E Namiecińska, M Grazul, B Sadowska… - Molecules, 2022 - mdpi.com
To meet the demand for alternatives to commonly used antibiotics, this paper evaluates the
antimicrobial potential of arene-ruthenium (II) complexes and their salts, which may be of …

Antioxidant and Antimicrobial Activity of Endophytyc Fungi Isolated from Syzygium aqueum Leaves

UH Habisukan, H Widjajanti, A Setiawan… - Journal of Physics …, 2021 - iopscience.iop.org
Syzygium aqueum is a widely used medicinal plant species with ethnomedicinal values.
Despite the plant, the endophytes are recognized as a rich source of secondary metabolites …

Preparation, in vitro and in silico Antioxidant and Antibacterial Studies of 4-Aminoacetanilide Azo Derivatives

AN Abd Halim, KW Yeo, NH Zamakshshari… - Journal of the Indian …, 2024 - Elsevier
ABSTRACT A new series of new 4-aminoacetanilide azo derivatives 1-13 were successfully
synthesized via a diazo coupling reaction and gave a good to excellent yield of 73%–93 …

4-Alkyliden-azetidinones modified with plant derived polyphenols: Antibacterial and antioxidant properties

D Giacomini, R Musumeci, P Galletti, G Martelli… - European journal of …, 2017 - Elsevier
Antimicrobial resistance is one of the major and growing concerns in hospital-and
community acquired infections, and new antimicrobial agents are therefore urgently …

Validated and rapid measurement of the ferric reducing antioxidant power in plasma samples

ML Gonzalez-Rivera, F Martinez-Morales… - Chemical Papers, 2018 - Springer
The ferric reducing antioxidant power assay was developed using rat plasma samples and
validated according to the Food and Drug Administration guidelines as well as strategies for …

[PDF][PDF] 加替沙星和司帕沙星的光动力抗菌研究

李圩田, 王佳雯, 洪阁, 毛丽娜, 刘天军 - 中国抗生素杂志, 2019 - zgkss.com.cn
目的喹诺酮作为抗菌药物在临床上具有一定的光敏毒副作用, 那么喹诺酮化合物是否可以作为
光敏抗菌药物应用呢? 基于上述目的我们研究了加替沙星(GFLX), 司帕沙星(SPFX) …