Pheochromocytoma and Paraganglioma Pheochromocytoma and paraganglioma are
related tumors that differ mainly in location; pheochromocytomas are adrenal, and …

Next-generation sequencing (NGS) technology has expanded in the last decades with
significant improvements in the reliability, sequencing chemistry, pipeline analyses, data …

Although the MYC oncogene has been implicated in cancer, a systematic assessment of
alterations of MYC, related transcription factors, and co-regulatory proteins, forming the …

Objective: The aim was to formulate clinical practice guidelines for pheochromocytoma and
paraganglioma (PPGL). Participants: The Task Force included a chair selected by the …

MYC regulates a complex biological program by transcriptionally activating and repressing
its numerous target genes. As such, MYC is a master regulator of many processes, including …

We performed massively parallel sequencing of paired tumor/normal samples from 203
multiple myeloma (MM) patients and identified significantly mutated genes and copy number …

A molecular biology–based taxonomy has been proposed for pheochromocytoma and
paraganglioma (PPGL). Data from the Cancer Genome Atlas revealed clinically relevant …

Transcription factor networks have evolved in order to control, coordinate, and separate, the
functions of distinct network modules spatially and temporally. In this review we focus on the …

Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that
arise from chromaffin cells of the adrenal medulla and the sympathetic/parasympathetic …

Genes in which germline mutations confer highly or moderately increased risks of cancer
are called cancer predisposition genes. More than 100 of these genes have been identified …