All molecules consist of chemical bonds, and much can be learned from mapping the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …

Conspectus Flow cytometry is a powerful tool with applications in diverse fields such as
microbiology, immunology, virology, cancer biology, stem cell biology, and metabolic …

Direct visualization of metabolic dynamics in living animals with high spatial and temporal
resolution is essential to understanding many biological processes. Here we introduce a …

Coherent Raman scattering (CRS) microscopy is a chemical imaging modality that provides
contrast based on intrinsic biomolecular vibrations. To date, endeavors on instrumentation …

Three-dimensional visualization of tissue structures using optical microscopy facilitates the
understanding of biological functions. However, optical microscopy is limited in tissue …

Stimulated Raman scattering (SRS) microscopy is a nonlinear optical imaging method for
visualizing chemical content based on molecular vibrational bonds. Featuring high speed …

We present a novel time-of-flight resolved Bessel light bullet-enabled stimulated Raman
scattering (B2-SRS) microscopy for deeper tissue 3D chemical imaging with high resolution …

Confocal Raman imaging can directly identify and visualise microplastics and even
nanoplastics. However, due to diffraction, the excitation laser spot has a size, which defines …

The light propagation in the medium normally experiences diffraction, dispersion, and
scattering. Studying the light propagation is a century-old problem as the photons may …

Chemical imaging offers critical information to understand the fundamentals in biology and
to assist clinical diagnostics. Label-free chemical imaging piques a general interest since it …