The Building Blocks of Antimicrobial Resistance in Pseudomonas aeruginosa: Implications for Current Resistance-Breaking Therapies

RF Langendonk, DR Neill, JL Fothergill - Frontiers in Cellular and …, 2021 - frontiersin.org
P. aeruginosa is classified as a priority one pathogen by the World Health Organisation, and
new drugs are urgently needed, due to the emergence of multidrug-resistant (MDR) strains …

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

MF Moradali, S Ghods, BHA Rehm - Frontiers in cellular and infection …, 2017 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Multidrug resistant bacteria in the community: trends and lessons learned

D Van Duin, D Paterson - Infectious disease clinics of North …, 2016 - pmc.ncbi.nlm.nih.gov
Multidrug resistant (MDR) bacteria are one of the most important current threats to public
health. Typically, MDR bacteria are associated with nosocomial infections. However, some …

The non-attached biofilm aggregate

KN Kragh, T Tolker-Nielsen, M Lichtenberg - Communications Biology, 2023 - nature.com
Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …

Multidrug‐resistant bacteria: their mechanism of action and prophylaxis

A Bharadwaj, A Rastogi, S Pandey… - BioMed research …, 2022 - Wiley Online Library
In the present scenario, resistance to antibiotics is one of the crucial issues related to public
health. Earlier, such resistance to antibiotics was limited to nosocomial infections, but it has …

Pseudomonas aeruginosa: all roads lead to resistance

EBM Breidenstein, C de la Fuente-Núñez… - Trends in …, 2011 - cell.com
Pseudomonas aeruginosa is often resistant to multiple antibiotics and consequently has
joined the ranks of 'superbugs' due to its enormous capacity to engender resistance. It …

Pseudomonas Aeruginosa: Resistance to the Max

K Poole - Frontiers in microbiology, 2011 - frontiersin.org
Pseudomonas aeruginosa is intrinsically resistant to a variety of antimicrobials and can
develop resistance during anti-pseudomonal chemotherapy both of which compromise …

A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence

D Balasubramanian, L Schneper, H Kumari… - Nucleic acids …, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

Metabolism and function of phenazines in bacteria: impacts on the behavior of bacteria in the environment and biotechnological processes

LS Pierson, EA Pierson - Applied microbiology and biotechnology, 2010 - Springer
Phenazines constitute a large group of nitrogen-containing heterocyclic compounds
produced by a diverse range of bacteria. Both natural and synthetic phenazine derivatives …

Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs—A Review

AM Sousa, MO Pereira - Pathogens, 2014 - mdpi.com
Pseudomonas aeruginosa is the most prevalent pathogen of cystic fibrosis (CF) lung
disease. Its long persistence in CF airways is associated with sophisticated mechanisms of …