Therapeutic cancer vaccines: past, present, and future
C Guo, MH Manjili, JR Subjeck, D Sarkar… - Advances in cancer …, 2013 - Elsevier
Therapeutic vaccines represent a viable option for active immunotherapy of cancers that aim
to treat late stage disease by using a patient's own immune system. The promising results …
to treat late stage disease by using a patient's own immune system. The promising results …
[HTML][HTML] Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications
DR Ciocca, SK Calderwood - Cell stress & chaperones, 2005 - ncbi.nlm.nih.gov
Heat shock proteins (Hsps) are overexpressed in a wide range of human cancers and are
implicated in tumor cell proliferation, differentiation, invasion, metastasis, death, and …
implicated in tumor cell proliferation, differentiation, invasion, metastasis, death, and …
Protein-based nanoparticles in cancer vaccine development
M Neek, TI Kim, SW Wang - Nanomedicine: Nanotechnology, Biology and …, 2019 - Elsevier
Peptide and protein-based cancer vaccines usually fail to elicit efficient immune responses
against tumors. However, delivery of these peptides and proteins as components within …
against tumors. However, delivery of these peptides and proteins as components within …
Induction of heat shock proteins in B-cell exosomes
A Clayton, A Turkes, H Navabi… - Journal of cell …, 2005 - journals.biologists.com
Exosomes are nanometer-sized vesicles secreted by a diverse range of live cells that
probably have physiological roles in modulating cellular immunity. The extracellular factors …
probably have physiological roles in modulating cellular immunity. The extracellular factors …
Extracellular HSPs: the complicated roles of extracellular HSPs in immunity
SK Calderwood, J Gong, A Murshid - Frontiers in immunology, 2016 - frontiersin.org
Extracellular heat-shock proteins (HSPs) interact with the immune system in a very complex
manner. Many such HSPs exert powerful effects on the immune response, playing both …
manner. Many such HSPs exert powerful effects on the immune response, playing both …
Heat‐shock proteins
Z Li, P Srivastava - Current protocols in immunology, 2003 - Wiley Online Library
Abstract Heat‐shock proteins (HSPs), or stress proteins, are highly conserved and present in
all organisms and in all cells of all organisms. Selected HSPs, also known as chaperones …
all organisms and in all cells of all organisms. Selected HSPs, also known as chaperones …
[HTML][HTML] Hyperthermia as an immunotherapy strategy for cancer
JJ Skitzki, EA Repasky, SS Evans - Current opinion in …, 2009 - ncbi.nlm.nih.gov
The use of hyperthermia as an adjunct to cancer immunotherapy is supported by an
increasing number of research data. Both preclinical and clinical data results have …
increasing number of research data. Both preclinical and clinical data results have …
Heat‐Shock Proteins
AT Hagymasi, JP Dempsey, PK Srivastava - Current Protocols, 2022 - Wiley Online Library
Abstract Heat‐shock proteins (HSPs), or stress proteins, are abundant and highly
conserved, present in all organisms and in all cells. Selected HSPs, also known as …
conserved, present in all organisms and in all cells. Selected HSPs, also known as …
The role of heat shock proteins in antigen cross presentation
A Murshid, J Gong, SK Calderwood - Frontiers in immunology, 2012 - frontiersin.org
Heat shock proteins (HSPs) are molecular chaperones that bind tumor antigens and
mediate their uptake into antigen presenting cells. HSP–antigen complexes are then …
mediate their uptake into antigen presenting cells. HSP–antigen complexes are then …
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis
Heat shock proteins (HSPs) are necessary for cancer cell survival. We identified a mutant of
HSP110 (HSP110ΔE9) in colorectal cancer showing microsatellite instability (MSI CRC) …
HSP110 (HSP110ΔE9) in colorectal cancer showing microsatellite instability (MSI CRC) …