In this review, we provide recent data on the role of mTOR kinase in the brain under
physiological conditions and after damage, with a particular focus on cerebral ischemia. We …

Exposure to drug-associated cues can induce drug craving and relapse in abstinent addicts.
Cue-induced craving that progressively intensifies (“incubates”) during withdrawal from …

Cerebral ischemia induces an inhibition of protein synthesis and causes cell death and
neuronal deficits. These deleterious effects do not occur in resilient areas of the brain, where …

Stress granules (SGs) are cytoplasmic ribonucleoprotein aggregates that are directly
connected with the translation initiation arrest response to cellular stresses. Translation …

Ischemic strokes are caused by a reduction in cerebral blood flow and both the ischemic
period and subsequent reperfusion induce brain injury, with different tissue damage …

Transient cerebral ischemia induces neuronal degeneration, followed in time by secondary
delayed neuronal death that is strongly correlated with a permanent inhibition of protein …

À la fois le sommeil et la privation de sommeil ont un impact sur la synthèse protéique au
niveau du cerveau, mais la contribution des mécanismes traductionnels à la régulation de …

The eukaryotic initiation factor (eIF) 4E-binding proteins (4E-BPs) regulate cap-dependent
protein translation and control the assembly of the eIF4F complex. In the present study, a …