Pathophysiological relevance of the cardiac β2-adrenergic receptor and its potential as a therapeutic target to improve cardiac function

J Pérez-Schindler, A Philp… - European journal of …, 2013 - Elsevier
β-adrenoceptors are members of the G protein-coupled receptor superfamily which play a
key role in the regulation of myocardial function. Their activation increases cardiac …

[HTML][HTML] The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes

B Tota, S Gentile, T Pasqua, E Bassino… - The FASEB …, 2012 - ncbi.nlm.nih.gov
Three forms of serpinin peptides, serpinin (Ala26Leu), pyroglutaminated (pGlu)-serpinin
(pGlu23Leu), and serpinin-Arg-Arg-Gly (Ala29Gly), are derived from cleavage at pairs of …

Salbutamol attenuates arrhythmogenic effect of aminophylline in a hPSC-derived cardiac model

D Kabanov, S Vrana Klimovic, D Beckerová… - Scientific Reports, 2024 - nature.com
The combination of aminophylline and salbutamol is frequently used in clinical practice in
the treatment of obstructive lung diseases. While the side effects (including arrhythmias) of …

Self-harm in adolescence and future mental health

K Hawton, RC O'Connor - The Lancet, 2012 - thelancet.com
Results of several school-based community studies have shown that self-harm (intentional
self-injury or self-poisoning) is very common in adolescents, being reported by around 10 …

Resveratrol enhances the inotropic effect but inhibits the proarrhythmic effect of sympathomimetic agents in rat myocardium

J Hernandez-Cascales - PeerJ, 2017 - peerj.com
Background Resveratrol is a cardioprotective agent with known antiarrhythmic effects that
has recently been shown to inhibit phosphodiesterase (PDE) enzyme activity. Thus, it is …

Synergistic, but not separate, stimulation of accumbal β1-and β2-adrenoceptors alters the accumbal dopamine efflux in freely moving rats

Y Aono, T Saigusa, H Taguchi, T Uchida… - European journal of …, 2013 - Elsevier
The effects of intra-accumbal infusion of selective agonists for the β-adrenoceptor subtypes
on the noradrenaline and dopamine efflux in the nucleus accumbens of freely moving rats …

β-agonists for ARDS: the dark side of adrenergic stimulation?

BT Thompson - The Lancet, 2012 - thelancet.com
β-agonists for ARDS: the dark side of adrenergic stimulation? - The Lancet Skip to Main Content
Advertisement The Lancet Journal This Journal Back Journal Home Online First Current Issue …

[PDF][PDF] Investigation into the cardiotoxic effects of β-adrenergic receptor agonists in myocardial ischaemia/reperfusion injury

AS Nagra - 2016 - pureportal.coventry.ac.uk
The human airways and lungs play a vital role in internal and external respiration, however
their ability to function correctly and efficiently can be impeded by various …