Background: The control of male fertility requires accurate endocrine, paracrine and
autocrine communications along the hypothalamus-pituitary-gonad (HPG) axis. In this …

Estrogen receptors alpha (ERα) and beta (ERβ) are transcription factors known to be
involved in the regulation of many complex physiological processes in mammals. They are …

Background The use of amoxicillin during early childhood has been associated with molar
incisor hypomineralization. Aim The objective of this study was to determine whether the use …

Kisspeptin, via Gpr54 receptor, regulates puberty onset in most vertebrates. Thus, the direct
involvement of kisspeptin activity in testis physiology was investigated in the anuran …

Exposure to 17β-trenbolone caused a skewed sex ratio in fish. However, the molecular
initiating event and key molecular event (s) remain unknown. In this study, zebrafish were …

Introduction. Wuzi Yanzong (WZYZ) formula, a famous traditional Chinese medicinal
prescription, has been widely used to treat kidney essence insufficiency‐induced …

An increasing number of studies revealed the importance of estrogen in male reproduction.
However, most research was conducted in laboratory rodents subjected to standardized …

In seasonal breeders, such as amphibians, testicular functions depend on complex
processes that change according to seasonality, including Leydig cell (LC) differentiation …

The gerbil, Gerbillus gerbillus, a nocturnal desert rodent of northern Africa, exhibits a
seasonal reproductive cycle with marked anatomical and behavioural shifts between …

In the frog Pelophylax esculentus, the endocannabinoid anandamide (AEA) modulates
Gonadotropin Releasing Hormone (GnRH) system in vitro and down-regulates …