Identifying the histologic subtypes and divergent differentiation in bladder cancer is
important to establish the correct diagnosis and classification and may also be clinically …

The current personalized oncology era has witnessed significant efforts to integrate clinical,
pathological, and molecular classifications. The growing need for molecular biomarkers to …

Abstract The Genitourinary Pathology Society (GUPS) undertook a critical review of the
recent advances in bladder cancer focusing on important topics of high interest for the …

The telomerase reverse transcriptase (TERT) promoter mutations are associated with
increased TERT mRNA and TERT protein levels, telomerase activity, and shorter but stable …

Purpose Recently discovered molecular classifications for urothelial bladder cancer
appeared to be promising prognostic and predictive biomarkers. The present study was …

Background Grading of muscle-invasive bladder cancer (MIBC) according to the current
World Health Organization (WHO) criteria is controversial due to its limited prognostic value …

Bladder cancer (BC) is a heterogeneous disease with highly variable clinical and
pathological features, and resulting in different outcomes. Such heterogeneity ensues from …

This study aimed to evaluate the diagnostic and prognostic roles of GATA-binding protein 3
(GATA3) immunohistochemistry in urothelial carcinoma (UC) using a meta-analysis. We …

Background: The most common bladder cancer (BC) histotype is pure urothelial carcinoma
(UC), which may undergo divergent differentiation in some cases. Variant histology (VH) …

Abstract Purpose of Review Molecular characterization of cancer allows us to understand
oncogenesis and clinical prognosis as well as facilitates development of biomarkers and …