Phthalate exposure and long-term epigenomic consequences: a review

S Dutta, DK Haggerty, DA Rappolee… - Frontiers in genetics, 2020 - frontiersin.org
Phthalates are esters of phthalic acid which are used in cosmetics and other daily personal
care products. They are also used in polyvinyl chloride (PVC) plastics to increase durability …

Exposure to an environmentally relevant phthalate mixture during prostate development induces microRNA upregulation and transcriptome modulation in rats

WR Scarano, A Bedrat, LG Alonso-Costa… - Toxicological …, 2019 - academic.oup.com
Environmental exposure to phthalates during intrauterine development might increase
susceptibility to neoplasms in reproductive organs such as the prostate. Although studies …

Endocrine‐disrupting effects of methylparaben on the adult gerbil prostate

JR Costa, MS Campos, RF Lima… - Environmental …, 2017 - Wiley Online Library
Parabens are xenoestrogens widely employed in cosmetics, foodstuffs, and pharmaceutical
products. These chemicals are known to disrupt hormone‐dependent organs, due to their …

Prostate hyperplasia caused by long‐term obesity is characterized by high deposition of extracellular matrix and increased content of MMP‐9 and VEGF

SA Silva, MG Gobbo, ME Pinto‐Fochi… - International journal …, 2015 - Wiley Online Library
Recent studies have shown a positive association of cancer and obesity, but the
morphological and molecular mechanisms involved in this relationship are still unknown …

[HTML][HTML] Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: proliferative and inflammatory disorders and a possible role of …

WR Scarano, FC de Toledo, MT Guerra… - Toxicology, 2009 - Elsevier
In the present study we evaluated the toxic effects on the male adult rat prostate of DBP
exposure during fetal and lactational periods, because although many studies have …

Lobe identity in the Mongolian gerbil prostatic complex: a new rodent model for prostate study

SS Rochel, A Bruni‐Cardoso… - … Record: Advances in …, 2007 - Wiley Online Library
Abstract Knowledge of structural and physiological differences among the prostatic lobes
(PL) is the basis for development of experimental studies in traditional laboratory rodents …

Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats

JZ Brandt, LTR Silveira, TF Grassi… - Reproductive …, 2014 - Elsevier
Bisphenol A (BPA) is a chemical that has been investigated for it potential to cause prostate
diseases. In this study, pregnant Sprague-Dawley rats were treated with 25 or 250 μg/kg …

Dietary fatty acid quality affects AR and PPARγ levels and prostate growth

ELO Escobar, MCC Gomes‐Marcondes… - The …, 2009 - Wiley Online Library
BACKGROUND Fatty acids are among the most important nutritional factors associated with
the ethiopathogenesis of prostate cancer, therefore the main objective of this work was to …

Neonatal exposure to MK-801, an N-methyl-D-aspartate receptor antagonist, enhances methamphetamine-induced locomotion and disrupts sensorimotor gating in …

T Uehara, T Sumiyoshi, T Seo, T Matsuoka, H Itoh… - Brain research, 2010 - Elsevier
Administration of non-competitive N-methyl-d-aspartate (NMDA) receptor antagonists (eg
phencyclidine, MK-801) has been shown to elicit behavioral abnormalities related to …

Prostatic morphological changes throughout life: Cytochemistry as a tool to reveal tissue aging markers

LHA Guerra, SGP Campos, SR Taboga… - Microscopy …, 2024 - Wiley Online Library
The prostate undergoes normal or pathological morphological changes throughout life. An
understanding of these changes is fundamental for the comprehension of aging‐related …