Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …

Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …

Background Currently, as the omicron variant of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) surges amid the coronavirus disease 2019 (COVID-19) …

Summary Infection with SARS‐CoV‐2, the etiology of the ongoing COVID‐19 pandemic, has
resulted in over 450 million cases with more than 6 million deaths worldwide, causing global …

Antibodies play a central role in the immune defense against SARS-CoV-2. Emerging
evidence has shown that nonneutralizing antibodies are important for immune defense …

A third vaccine dose is often required to achieve potent, long-lasting immune responses. We
investigated the effect of three 8-μg doses of CVnCoV, CureVac's severe acute respiratory …

Serological tests detect antibodies generated by infection or vaccination, and are
indispensable tools along different phases of a pandemic, from early monitoring of pathogen …

We report the application of ancestral sequence reconstruction on coronavirus spike protein,
resulting in stable and highly soluble ancestral scaffold antigens (AnSAs). The AnSAs …

Neutralizing antibodies correlate with protection against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). Recent studies, however, show that binding antibody titers, in …

Recent studies show an important role for non-neutralizing anti-spike antibodies, including
monoclonal antibodies (mAbs), in robustly protecting against SARS-CoV-2 infection. These …