[HTML][HTML] Neuroplastic changes following brain ischemia and their contribution to stroke recovery: novel approaches in neurorehabilitation

C Alia, C Spalletti, S Lai, A Panarese… - Frontiers in cellular …, 2017 - frontiersin.org
Ischemic damage to the brain triggers substantial reorganization of spared areas and
pathways, which is associated with limited, spontaneous restoration of function. A better …

[HTML][HTML] Advanced neurotechnologies for the restoration of motor function

S Micera, M Caleo, C Chisari, FC Hummel, A Pedrocchi - Neuron, 2020 - cell.com
Stroke is one of the leading causes of long-term disability. Advanced technological solutions
(" neurotechnologies") exploiting robotic systems and electrodes that stimulate the nervous …

Rehabilitation and plasticity following stroke: insights from rodent models

M Caleo - Neuroscience, 2015 - Elsevier
Ischemic injuries within the motor cortex result in functional deficits that may profoundly
impact activities of daily living in patients. Current rehabilitation protocols achieve only …

[HTML][HTML] Reducing GABAA-mediated inhibition improves forelimb motor function after focal cortical stroke in mice

C Alia, C Spalletti, S Lai, A Panarese, S Micera… - Scientific Reports, 2016 - nature.com
A deeper understanding of post-stroke plasticity is critical to devise more effective
pharmacological and rehabilitative treatments. The GABAergic system is one of the key …

[HTML][HTML] Combined rehabilitation promotes the recovery of structural and functional features of healthy neuronal networks after stroke

ALA Mascaro, E Conti, S Lai, AP Di Giovanna… - Cell reports, 2019 - cell.com
Rehabilitation is considered the most effective treatment for promoting the recovery of motor
deficits after stroke. One of the most challenging experimental goals is to unambiguously link …

Preclinical upper limb neurorobotic platform to assess, rehabilitate, and develop therapies

M Pasquini, ND James, I Dewany, FV Coen, N Cho… - Science Robotics, 2022 - science.org
Numerous neurorehabilitative, neuroprosthetic, and repair interventions aim to address the
consequences of upper limb impairments after neurological disorders. Although these …

[HTML][HTML] Combining robotic training and inactivation of the healthy hemisphere restores pre-stroke motor patterns in mice

C Spalletti, C Alia, S Lai, A Panarese, S Conti, S Micera… - Elife, 2017 - elifesciences.org
Focal cortical stroke often leads to persistent motor deficits, prompting the need for more
effective interventions. The efficacy of rehabilitation can be increased by 'plasticity …

[HTML][HTML] Combined adipose tissue-derived mesenchymal stem cell therapy and rehabilitation in experimental stroke

J Mu, A Bakreen, M Juntunen, P Korhonen… - Frontiers in …, 2019 - frontiersin.org
Background/Objective: Stroke is a leading global cause of adult disability. As the population
ages as well as suffers co-morbidities, it is expected that the stroke burden will increase …

Quantitative kinematic characterization of reaching impairments in mice after a stroke

S Lai, A Panarese, C Spalletti, C Alia… - … and neural repair, 2015 - journals.sagepub.com
Background and Objective. Kinematic analysis of reaching movements is increasingly used
to evaluate upper extremity function after cerebrovascular insults in humans and has also …

[HTML][HTML] Experimental and computational study on motor control and recovery after stroke: toward a constructive loop between experimental and virtual embodied …

AL Allegra Mascaro, E Falotico, S Petkoski… - Frontiers in systems …, 2020 - frontiersin.org
Being able to replicate real experiments with computational simulations is a unique
opportunity to refine and validate models with experimental data and redesign the …