Intracytoplasmic sperm injection for male infertility and consequences for offspring

SC Esteves, M Roque, G Bedoschi, T Haahr… - Nature Reviews …, 2018 - nature.com
Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

Advances in sperm analysis: techniques, discoveries and applications

C Dai, Z Zhang, G Shan, LT Chu, Z Huang… - Nature Reviews …, 2021 - nature.com
Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally,
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …

Improving ICSI: A review from the spermatozoon perspective

M Simopoulou, L Gkoles, P Bakas… - Systems biology in …, 2016 - Taylor & Francis
Intracytoplasmic sperm injection (ICSI) is the most frequently applied method for fertilization
making the process of identifying the perfect spermatozoon fundamental. Herein we offer a …

Sperm selection during ICSI treatments reduces single-but not double-strand DNA break values compared to the semen sample

S Lara-Cerrillo, J Ribas-Maynou… - Journal of Assisted …, 2021 - Springer
Purpose To detect a possible bias in sperm DNA fragmentation (SDF) testing when
performed on semen samples or on those few spermatozoa selected for Intracytoplasmic …

New horizons in human sperm selection for assisted reproduction

B Nixon, JE Schjenken, ND Burke… - Frontiers in …, 2023 - frontiersin.org
Male infertility is a commonly encountered pathology that is estimated to be a contributory
factor in approximately 50% of couples seeking recourse to assisted reproductive …

[HTML][HTML] Evaluation of sperm DNA fragmentation using multiple methods: a comparison of their predictive power for male infertility

A Javed, MS Talkad, MK Ramaiah - Clinical and experimental …, 2019 - ncbi.nlm.nih.gov
Objective The usual seminal profile has been customarily used for diagnosing male infertility
based on an examination of semen samples. However, sperm DNA fragmentation has also …

[HTML][HTML] What is the importance of sperm subpopulations?

F Martínez-Pastor - Animal Reproduction Science, 2022 - Elsevier
The study of sperm subpopulations spans three decades. The origin, meaning, and practical
significance, however, are less clear. Current technology for assessing sperm morphology …

The relevance of sperm morphology in male infertility

E Moretti, C Signorini, D Noto, R Corsaro… - … in Reproductive Health, 2022 - frontiersin.org
This brief report concerns the role of human sperm morphology assessment in different
fields of male infertility: basic research, genetics, assisted reproduction technologies …

Clinical factors associated with sperm DNA fragmentation in male patients with infertility

A Komiya, T Kato, Y Kawauchi… - The scientific world …, 2014 - Wiley Online Library
Objective. The clinical factors associated with sperm DNA fragmentation (SDF) were
investigated in male patients with infertility. Materials and Methods. Fifty‐four ejaculates from …