[HTML][HTML] Intranasal delivery of nanostructured lipid carriers, solid lipid nanoparticles and nanoemulsions: A current overview of in vivo studies

CP Costa, JN Moreira, JMS Lobo, AC Silva - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The management of the central nervous system (CNS) disorders is challenging, due to the
need of drugs to cross the blood‒brain barrier (BBB) and reach the brain. Among the …

Advances in edible nanoemulsions: Digestion, bioavailability, and potential toxicity

DJ McClements - Progress in lipid research, 2021 - Elsevier
The design, fabrication, and application of edible nanoemulsions for the encapsulation and
delivery of bioactive agents has been a highly active research field over the past decade or …

Synthesis and potential applications of lipid nanoparticles in medicine

E Musielak, A Feliczak-Guzik, I Nowak - Materials, 2022 - mdpi.com
Currently, carriers of active ingredients in the form of particles of a size measured in
nanometers are the focus of interest of research centers worldwide. So far, submicrometer …

[HTML][HTML] Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration

VN Thuy, TV Van, AH Dao, BJ Lee - OpenNano, 2022 - Elsevier
Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

Perspectives and prospective on solid lipid nanoparticles as drug delivery systems

OA Madkhali - Molecules, 2022 - mdpi.com
Combating multiple drug resistance necessitates the delivery of drug molecules at the
cellular level. Novel drug delivery formulations have made it possible to improve the …

Particle size reduction techniques of pharmaceutical compounds for the enhancement of their dissolution rate and bioavailability

R Kumar, AK Thakur, P Chaudhari… - Journal of Pharmaceutical …, 2022 - Springer
In pharmaceutical research and development, various new chemical entities (NCE) are
found to be poorly water-soluble. Therefore, solubility enhancement, a key factor for higher …

Nanoformulations as a strategy to overcome the delivery limitations of cannabinoids

TS Reddy, R Zomer, N Mantri - Phytotherapy Research, 2023 - Wiley Online Library
Medical cannabis has received significant interest in recent years due to its promising
benefits in the management of pain, anxiety, depression and neurological and movement …

Solid lipid nanoparticles: a versatile approach for controlled release and targeted drug delivery

M Munir, M Zaman, MA Waqar, MA Khan… - Journal of Liposome …, 2024 - Taylor & Francis
Abstract Solid Lipid Nanoparticles (SLN), the first type of lipid-based solid carrier systems in
the nanometer range, were introduced as a replacement for liposomes. SLN are aqueous …

The emerging role of ionic liquid-based approaches for enhanced skin permeation of bioactive molecules: a snapshot of the past couple of years

A Gomes, L Aguiar, R Ferraz, C Teixeira… - International Journal of …, 2021 - mdpi.com
Topical and transdermal delivery systems are of undeniable significance and ubiquity in
healthcare, to facilitate the delivery of active pharmaceutical ingredients, respectively, onto …

Therapeutic potential of lipid nanosystems for the treatment of Parkinson's disease

S Preetam, S Jonnalagadda, L Kumar, R Rath… - Ageing Research …, 2023 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder. The
degeneration of dopaminergic neurons in the midbrain is primarily responsible for the onset …