[HTML][HTML] Periodontal disease: the good, the bad, and the unknown

LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

Periodontitis and accelerated biological aging: A geroscience approach

G Baima, M Romandini, F Citterio… - Journal of Dental …, 2022 - journals.sagepub.com
As the whole world is epidemically aging, the burden of periodontitis and tooth loss is
becoming a major health concern. Growing meta-epidemiological data implicate chronic …

Severe COVID-19 lung infection in older people and periodontitis

R Aquino-Martinez, S Hernández-Vigueras - Journal of Clinical Medicine, 2021 - mdpi.com
Periodontal bacteria dissemination into the lower respiratory tract may create favorable
conditions for severe COVID-19 lung infection. Once lung tissues are colonized, cells that …

The association between oxidative balance score and periodontitis in adults: a population-based study

H Qu - Frontiers in Nutrition, 2023 - frontiersin.org
Introduction The pathogenesis between oxidative stress and periodontitis was correlated.
The Oxidative Balance Score (OBS) is a systematic tool to assess the effects of diet and …

Porphyromonas gingivalis Provokes Exosome Secretion and Paracrine Immune Senescence in Bystander Dendritic Cells

R Elsayed, M Elashiry, Y Liu, A El-Awady… - Frontiers in cellular …, 2021 - frontiersin.org
Periodontitis is a disease of ageing or inflammaging, and is comorbid with other more
severe age-related chronic diseases. With advanced age comes an increase in …

Rejuvenation of mesenchymal stem cells to ameliorate skeletal aging

M Cheng, W Yuan, A Moshaverinia, B Yu - Cells, 2023 - mdpi.com
Advanced age is a shared risk factor for many chronic and debilitating skeletal diseases
including osteoporosis and periodontitis. Mesenchymal stem cells develop various aging …

Senescent CD4+CD28 T Lymphocytes as a Potential Driver of Th17/Treg Imbalance and Alveolar Bone Resorption during Periodontitis

L González-Osuna, A Sierra-Cristancho… - International Journal of …, 2022 - mdpi.com
Senescent cells express a senescence-associated secretory phenotype (SASP) with a pro-
inflammatory bias, which contributes to the chronicity of inflammation. During chronic …

Molecular mechanisms of periodontal disease

M Kajiya, H Kurihara - International Journal of Molecular Sciences, 2021 - mdpi.com
Periodontal disease, one of the most prevalent human infectious diseases, is characterized
by chronic inflammatory tissue destruction of the alveolar bone and the connective tissues …

Does periodontitis influence the risk of COVID‐19? A scoping review

A Ghosh, B Joseph, S Anil - Clinical and Experimental Dental …, 2022 - Wiley Online Library
Objective Research has shown that the novel severe acute respiratory syndrome
coronavirus‐2 (SARS‐CoV‐2) significantly influences the oral microbiome to expedite …

Molecular profiling of intrabony defects' gingival crevicular fluid

VP Koidou, E Hagi‐Pavli, S Cross… - Journal of …, 2022 - Wiley Online Library
Aim To profile, for the first time, the gingival crevicular fluid (GCF) of intrabony defects
against a wide array of inflammatory and regenerative markers. Materials and methods …