Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas

J Welander, P Söderkvist… - Endocrine-related cancer, 2011 - erc.bioscientifica.com
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare neuroendocrine tumors
of the adrenal glands and the sympathetic and parasympathetic paraganglia. They can …

Consensus statement on next-generation-sequencing-based diagnostic testing of hereditary phaeochromocytomas and paragangliomas

NGS in PPGL (NGSnPPGL) Study Group… - Nature Reviews …, 2017 - nature.com
Phaeochromocytomas and paragangliomas (PPGLs) are neural-crest-derived tumours of
the sympathetic or parasympathetic nervous system that are often inherited and are …

Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline

JWM Lenders, QY Duh, G Eisenhofer… - The Journal of …, 2014 - academic.oup.com
Objective: The aim was to formulate clinical practice guidelines for pheochromocytoma and
paraganglioma (PPGL). Participants: The Task Force included a chair selected by the …

Head and neck paragangliomas: an update on evaluation and management

MG Moore, JL Netterville… - … --Head and Neck …, 2016 - journals.sagepub.com
Objective Head and neck paragangliomas are a group of slow-growing hypervascular
tumors associated with the paraganglion system. The approach to evaluate and treat these …

An update on the genetics of paraganglioma, pheochromocytoma, and associated hereditary syndromes

AP Gimenez-Roqueplo, PL Dahia… - Hormone and …, 2012 - thieme-connect.com
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are catecholamine-secreting
tumors of neural crest origin. Once collectively known as the '10% tumor', based on the …

Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma

G Eisenhofer, JWM Lenders, H Timmers… - Clinical …, 2011 - academic.oup.com
BACKGROUND Pheochromocytomas are rare catecholamine-producing tumors derived in
more than 30% of cases from mutations in 9 tumor-susceptibility genes identified to date …

[HTML][HTML] Multiple endocrine neoplasia type 2: an overview

J Moline, C Eng - Genetics in medicine, 2011 - Elsevier
Multiple endocrine neoplasia type 2 is historically composed of three clinical subtypes, all of
which are associated with germline mutations in the RET proto-oncogene. Multiple …

TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors

U Tabori, A Shlien, B Baskin, S Levitt, P Ray… - Journal of clinical …, 2010 - ascopubs.org
Purpose Choroid plexus carcinomas are pediatric tumors with poor survival rates and a
strong, but poorly understood, association with Li-Fraumeni syndrome (LFS). Currently, with …

Pheochromocytoma: a review

A Tsirlin, Y Oo, R Sharma, A Kansara, A Gliwa… - Maturitas, 2014 - Elsevier
Pheochromocytomas are catecholamine producing neuroendocrine tumors that can be
adrenal or extra-adrenal in origin. The classic symptoms of pheochromocytoma are …

Recommendations for somatic and germline genetic testing of single pheochromocytoma and paraganglioma based on findings from a series of 329 patients

M Currás-Freixes, L Inglada-Pérez… - Journal of medical …, 2015 - jmg.bmj.com
Background Nowadays, 65–80% of pheochromocytoma and paraganglioma (PPGL) cases
are explained by germline or somatic mutations in one of 22 genes. Several genetic testing …