Micromolar Affinity and Higher: Synthetic Host–Guest Complexes with High Stabilities

S Sarkar, P Ballester, M Spektor… - Angewandte Chemie …, 2023 - Wiley Online Library
The design of high‐affinity synthetic host–guest complexes is of paramount importance
because they are key elements in constructing unprecedented supramolecular assemblies …

Solvent effects in anion recognition

SC Patrick, PD Beer, JJ Davis - Nature Reviews Chemistry, 2024 - nature.com
Anion recognition is pertinent to a range of environmental, medicinal and industrial
applications. Recent progress in the field has relied on advances in synthetic host design to …

A hexapodal capsule for the recognition of anions

H Xie, TJ Finnegan… - Journal of the …, 2021 - ACS Publications
We herein describe the preparation, characterization, and recognition characteristics of
novel hexapodal capsule 1 composed of two benzenes joined by six hydrogen bonding …

Revealing the hidden costs of organization in host–guest chemistry using chloride-binding foldamers and their solvent dependence

FC Parks, EG Sheetz, SR Stutsman… - Journal of the …, 2022 - ACS Publications
Preorganization is a key concept in supramolecular chemistry. Preorganized receptors
enhance binding by minimizing the organization costs associated with adopting the …

Polarity-tolerant chloride binding in foldamer capsules by programmed solvent-exclusion

Y Liu, FC Parks, EG Sheetz, CH Chen… - Journal of the American …, 2021 - ACS Publications
Persistent anion binding in a wide range of solution environments is a key challenge that
continues to motivate and demand new strategies in synthetic receptor design. Though …

Engineered binding microenvironments in halogen bonding polymers for enhanced anion sensing

KM Bąk, SC Patrick, X Li, PD Beer… - Angewandte …, 2023 - Wiley Online Library
Mimicking Nature's polymeric protein architectures by designing hosts with binding cavities
screened from bulk solvent is a promising approach to achieving anion recognition in …

[2+ 3] Amide cages by oxidation of [2+ 3] imine cages–revisiting molecular hosts for highly efficient nitrate binding

JC Lauer, AS Bhat, C Barwig, N Fritz… - … A European Journal, 2022 - Wiley Online Library
The pollution of groundwater with nitrate is a serious issue because nitrate can cause
several diseases such as methemoglobinemia or cancer. Therefore, selective removal of …

Solvent Acts as the Referee in a Match‐Up Between Charged and Preorganized Receptors

N Bhattacharjee, X Gao, A Nathani… - … A European Journal, 2023 - Wiley Online Library
The prevalence of anion‐cation contacts in biomolecular recognition under aqueous
conditions suggests that ionic interactions should dominate the binding of anions in solvents …

Supramolecular umpolung: Converting electron-rich resorcin [4] arenes into potent CH-bonding anion receptors and transporters

ER Abdurakhmanova, D Mondal, H Jędrzejewska… - Chem, 2024 - cell.com
CH hydrogen bonding receptors constitute an emerging class of anion sensors and
transporters, which, owing to their high proteolytic and pH resistance, are promising for …

Disrupting the Hofmeister bias in salt liquid–liquid extraction with an arylethynyl bisurea anion receptor

HA Fargher, LH Delmau, VS Bryantsev, MM Haley… - Chemical …, 2024 - pubs.rsc.org
Host-mediated liquid–liquid extraction is a convenient method for the separation of inorganic
salts. However, selective extraction of an anion, regardless of its hydrophilicity or lipophilicity …