The tumor microenvironment plays a critical role in cancer development, progression, and
control. The molecular and cellular nature of the tumor immune microenvironment influences …

Particle based adjuvant showed promising signs on delivering antigen to immune cells and
acting as stimulators to elicit preventive or therapeutic response. Nevertheless, the wide size …

Cancer is still one of the most serious threats to human worldwide. Aberrant patterns of
glycosylation on the surface of cancer cells, which are correlated with various cancer …

Dendritic cells (DCs) present internalized antigens to CD8 T cells through cross-
presentation by major histocompatibility complex class I (MHC-I) molecules. While …

Dendritic cell (DC) vaccines hold great potential in cancer immunotherapy, but the
suboptimal design of DC vaccines and the immunosuppressive tumor microenvironment …

Approaches to treat cancer with therapeutic vaccination have made significant progress. In
order to induce efficient antitumor immunity, a vaccine should target and activate antigen …

The immune system, interacting intimately with the cancer cells in a tumor, may combat or
favor cancer development and progression, or both. One of the most important risk factors for …

We explored an intelligent vaccine system via facile approaches using both experimental
and theoretical techniques based on the two-dimensional graphene oxide (GO). Without …

The reactivation of human cytomegalovirus (HCMV) poses a serious health threat to immune
compromised individuals. As a treatment strategy, dendritic cell (DC) vaccination trials are …

Primary immunodeficiency disorders (PIDs) convey increased susceptibility to infections and
sometimes to malignancies, particularly lymphomas. Such cancer development can be …