The spatial and temporal development of the brain, overlying meninges (fibroblasts,
vasculature and immune cells) and calvarium are highly coordinated. In particular, the timing …

Microenvironmental factors are known fundamental regulators of the phenotype and
aggressiveness of glioblastoma (GBM), the most lethal brain tumor, characterized by fast …

Sleep is vital for human health and has a moderate heritability. Previous genome-wide
association studies have limitations in capturing the role of rare genetic variants in sleep …

Essential for brain formation and protective against tauopathy, activity-dependent
neuroprotective protein (ADNP) is critical for neurogenesis and cognitive functions, while …

Angelman syndrome (AS) is a rare neurogenetic disorder caused by UBE3A deficiency and
characterized by severe developmental delay, cognitive impairment, and motor dysfunction …

First Person is a series of interviews with the first authors of a selection of papers published
in Disease Models & Mechanisms, helping researchers promote themselves alongside their …

Abstract The gene CELSR3 (Cadherin EGF LAG Seven-pass-G-type Receptor 3) has been
recently recognized as a high-confidence risk factor for Tourette syndrome (TS). Additionally …

The positive effects of exercise in maintaining both physical and cognitive health have been
widely established during the past few decades. In addition to alleviating the risk of …