Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …

NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …

Doxorubicin (DOX) is one of the widely used anti-tumor drugs. However, DOX-induced
cardiotoxicity (DIC) and hepatotoxicity (DIH) are among the side effects that limited its …

TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene
expression. Dysregulation of their activity is associated with many serious pathogenic states …

Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …

The oncogenic chemokine duo CXCR4-CXCL12/SDF-1 (CXC Receptor 4-CXC Ligand
12/Stromal-derived factor 1) has been the topic of intense scientific disquisitions since Muller …

Glioblastoma multiforme (GBM) is the most common and invasive primary central nervous
system tumor in humans, accounting for approximately 45–50% of all primary brain tumors …

Background The molecular mechanism of the significant role of long noncoding RNAs
(lncRNAs) in the progression and metastasis of gastric cancer (GC) remains largely elusive …

Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …

Chemokines are small secreted proteins that regulate the immune system by signaling
through chemokine receptors to induce immune cell migration, motility, and infiltration into …