Recent progress in gene therapy to deliver nucleic acids with multivalent cationic vectors
E Junquera, E Aicart - Advances in colloid and interface science, 2016 - Elsevier
Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …
cationic non-viral vectors have received special attention in the last decade. Much effort has …
Current designs of polymeric platforms towards the delivery of nucleic acids inside the cells with focus on polyethylenimine
FA de Oliveira, LJC Albuquerque… - Current Gene …, 2021 - ingentaconnect.com
Background: Gene delivery is a promising technology for treating diseases linked to
abnormal gene expression. Since nucleic acids are the therapeutic entities in such …
abnormal gene expression. Since nucleic acids are the therapeutic entities in such …
Nucleic acids based polyelectrolyte complexes: Their complexation mechanism, morphology, and stability
YH Kim, K Lee, S Li - Chemistry of Materials, 2021 - ACS Publications
Nucleic acids are a special class of negatively charged polymers, and they can complex with
cationic small molecules and polymers to form polyelectrolyte complexes of rich …
cationic small molecules and polymers to form polyelectrolyte complexes of rich …
[HTML][HTML] Magnetoresponsive biocomposite hydrogels comprising gelatin and valine based magnetic ionic liquid surfactant as controlled release nanocarrier for drug …
The utilization of biopolymer hydrogels has been challenging due to the lack of
controllability, actuation, and quick-response properties. Herein, we report a strategic …
controllability, actuation, and quick-response properties. Herein, we report a strategic …
Amphiphilic Biodegradable PEG-PCL-PEI Triblock Copolymers for FRET-Capable in Vitro and in Vivo Delivery of siRNA and Quantum Dots
T Endres, M Zheng, A Kılıç, A Turowska… - Molecular …, 2014 - ACS Publications
Amphiphilic triblock copolymers represent a versatile delivery platform capable of co-
delivery of nucleic acids, drugs, and/or dyes. Multifunctional cationic triblock copolymers …
delivery of nucleic acids, drugs, and/or dyes. Multifunctional cationic triblock copolymers …
Polyelectrolyte complexes of DNA and linear PEI: formation, composition and properties
IY Perevyazko, M Bauer, GM Pavlov, S Hoeppener… - Langmuir, 2012 - ACS Publications
In the present study, the complexation between linear 13.4 kDa poly (ethylene imine)(LPEI)
and plasmid DNA was investigated. Analytical ultracentrifugation (AUC) was used for size …
and plasmid DNA was investigated. Analytical ultracentrifugation (AUC) was used for size …
AAV2 production with optimized N/P ratio and PEI-mediated transfection results in low toxicity and high titer for in vitro and in vivo applications
X Huang, AV Hartley, Y Yin, JH Herskowitz… - Journal of virological …, 2013 - Elsevier
The adeno-associated virus (AAV) is one of the most useful viral vectors for gene delivery for
both in vivo and in vitro applications. A variety of methods have been established to produce …
both in vivo and in vitro applications. A variety of methods have been established to produce …
Magnetic proline-based ionic liquid surfactant as a nano-carrier for hydrophobic drug delivery
Magnetic proline-based surface-active ionic liquid ([ProC10][FeCl3Br]) have been
synthesized and investigated for their application in hydrophobic drug delivery. Hydrophobic …
synthesized and investigated for their application in hydrophobic drug delivery. Hydrophobic …
[HTML][HTML] A simple distance paper-based analytical device for the screening of lead in food matrices
K Katelakha, V Nopponpunth, W Boonlue… - Biosensors, 2021 - mdpi.com
A simple and rapid distance paper-based analytical device (dPAD) for the detection of lead
(Pb) in foods is proposed herein. The assay principle is based on competitive binding …
(Pb) in foods is proposed herein. The assay principle is based on competitive binding …
Preparation and characterization of liposome-encapsulated plasmid DNA for gene delivery
The success of common nonviral gene delivery vehicles, lipoplexes and polyplexes, is
limited by the toxicity and instability of these charged molecules. Stealth liposomes could …
limited by the toxicity and instability of these charged molecules. Stealth liposomes could …