Poly (2-oxazoline) s based biomaterials: A comprehensive and critical update

T Lorson, MM Luebtow, E Wegener, MS Haider… - Biomaterials, 2018 - Elsevier
Abstract Poly (2-oxazoline) s have been investigated for decades as biomaterials.
Pioneering early work suggested that hydrophilic poly (2-oxazoline) s are comparable to …

Polyoxazoline: A review article from polymerization to smart behaviors and biomedical applications

SN Mahand, S Aliakbarzadeh, A Moghaddam… - European Polymer …, 2022 - Elsevier
Abstract Poly (2-oxazoline) s are emerging innovative biomaterials that show analogous and
even preferable properties compared to well-known counterparts, especially poly (ethylene …

The chemistry of poly (2-oxazoline) s

B Verbraeken, BD Monnery, K Lava… - European Polymer …, 2017 - Elsevier
As we celebrate the 50th birthday of the discovery of poly (2-alkyl/aryl-2-oxazoline) s (PAOx)
this year we see a research field that is rapidly expanding after some lesser academic …

Poly (2‐oxazoline)‐and Poly (2‐oxazine)‐Based Self‐Assemblies, Polyplexes, and Drug Nanoformulations—An Update

A Zahoranová, R Luxenhofer - Advanced Healthcare Materials, 2021 - Wiley Online Library
Abstract For many decades, poly (2‐oxazoline) s and poly (2‐oxazine) s, two closely related
families of polymers, have led the life of a rather obscure research topic with only a few …

Full and partial hydrolysis of poly (2-oxazoline) s and the subsequent post-polymerization modification of the resulting polyethylenimine (co) polymers

MA Mees, R Hoogenboom - Polymer Chemistry, 2018 - pubs.rsc.org
The synthesis of linear polyethylenimine (L-PEI) is mostly performed via the acidic or basic
hydrolysis of poly (2-alkyl-2-oxazoline) s (PAOx). Besides full hydrolysis leading to L-PEI, the …

The concept of bio-corona in modulating the toxicity of engineered nanomaterials (ENM)

D Westmeier, RH Stauber, D Docter - Toxicology and applied …, 2016 - Elsevier
Besides the wide use of engineered nanomaterials (ENM) in technical products, their
application spectrum in biotechnology and biomedicine is steadily increasing. In complex …

Recent advances and prospects in nano drug delivery systems using lipopolyoxazolines

L Simon, N Marcotte, JM Devoisselle, S Begu… - International journal of …, 2020 - Elsevier
Facing the growing demand in nano drug delivery systems (nDDS), hybrid excipients based
on natural molecules and well-defined synthetic polymers are intensively investigated …

Tuning the surface of nanoparticles: impact of poly (2‐ethyl‐2‐oxazoline) on protein adsorption in serum and cellular uptake

O Koshkina, D Westmeier, T Lang… - Macromolecular …, 2016 - Wiley Online Library
Due to the adsorption of biomolecules, the control of the biodistribution of nanoparticles is
still one of the major challenges of nanomedicine. Poly (2‐ethyl‐2‐oxazoline)(PEtOx) for …

3rd generation poly (ethylene imine) s for gene delivery

T Bus, C Englert, M Reifarth, P Borchers… - Journal of Materials …, 2017 - pubs.rsc.org
Cationic polymers play a crucial role within the field of gene delivery offering the possibility
to circumvent (biological) barriers in an elegant way. However, polymers are accompanied …

Thermoresponsive polyoxazolines as vectors for transfection of nucleic acids

E Haladjova, S Rangelov, C Tsvetanov - Polymers, 2020 - mdpi.com
Poly (2-oxazoline) s (POx) are an attractive platform for the development of non-viral gene
delivery systems. The combination of POx moieties, exhibiting excellent biocompatibility …