Metabolomics analysis reveals amelioration effects of yellowhorn tea extract on hyperlipidemia, inflammation, and oxidative stress in high-fat diet-fed mice

N Ta, EE, R Qi, X Mu, L Feng, G Ba, Y Li… - Frontiers in …, 2023 - frontiersin.org
Yellowhorn tea (YT) is traditionally used as a lipid-lowering beverage in Mongolian
minorities. However, the pharmacological effects of YT extract and its specific metabolic …

Medicinal chemistry-based perspective on thiophene and its derivatives: Exploring the structural insights to discover plausible druggable leads

S Thakur, D Kumar, KK Goel, P Rawat… - RSC Medicinal …, 2024 - pubs.rsc.org
Thiophene is a privileged pharmacophore in medicinal chemistry owing to its diversified
biological attributes. The thiophene moiety has been ranked 4th in US FDA drug approval of …

Effects of High-altitude Hypoxia on Drug Metabolism and Pharmacokinetics of Sedative-hypnotic Drugs and Regulatory Mechanism

L Tian, G Liu, J Han, X Li - Current Drug Metabolism, 2024 - benthamdirect.com
Sedative hypnotics effectively improve sleep quality under high-altitude hypoxia by reducing
central nervous system excitability. High-altitude hypoxia causes sleep disorders and …

Metabolic Profile Analysis of Designer Benzodiazepine Etizolam in Zebrafish and Human Liver Microsomes

Z Jie, S Qin, W Zhang, J Wang, J Lu, G Qin, X Hou… - Metabolites, 2023 - mdpi.com
As one of the most widely abused designer benzodiazepines worldwide, Etizolam is
characterized by its high addiction potential, low production cost, and difficulty in detection …

Analysis on dynamic changes of etizolam and its metabolites and exploration of its development prospect using UPLC-Q-exactive-MS

Z Jie, S Qin, F Liu, D Xu, J Sun, G Qin, X Hou… - … of Pharmaceutical and …, 2024 - Elsevier
As one of the most widely abused designer benzodiazepines in the world, etizolam has
been found in many cases in many countries. In this study, UPLC-Q-Exactive-MS was used …

Recent findings and advancements in the detection of designer benzodiazepines: a brief review

D Wu, L Fu - Archives of Industrial Hygiene and Toxicology, 2023 - sciendo.com
This review article takes a closer look at a new class of psychoactive substances called
designer benzodiazepines (DBZs) and the challenges of their detection. These are …

Nove spoznaje i napredak u otkrivanju dizajnerskih benzodiazepina–kratak pregled

D Wu, L Fu - Arhiv za higijenu rada i toksikologiju, 2023 - hrcak.srce.hr
Sažetak Svrha je ovoga preglednog članka dati bolji uvid u djelovanje nove skupine
psihoaktivnih tvari zvanih dizajnerski benzodiazepini (DBZ) iu izazove njihova otkrivanja …