[HTML][HTML] Medical image-based computational fluid dynamics and fluid-structure interaction analysis in vascular diseases

Y He, H Northrup, H Le, AK Cheung… - … in Bioengineering and …, 2022 - frontiersin.org
Hemodynamic factors, induced by pulsatile blood flow, play a crucial role in vascular health
and diseases, such as the initiation and progression of atherosclerosis. Computational fluid …

Pathophysiological, cellular, and molecular events of the vascular system in anaphylaxis

E Nuñez-Borque, S Fernandez-Bravo… - Frontiers in …, 2022 - frontiersin.org
Anaphylaxis is a systemic hypersensitivity reaction that can be life threatening.
Mechanistically, it results from the immune activation and release of a variety of mediators …

Microstructural and mechanical characterization of the layers of human descending thoracic aortas

M Amabili, M Asgari, ID Breslavsky, G Franchini… - Acta Biomaterialia, 2021 - Elsevier
The mechanical properties of human aortas are linked to the layered tissue and its
microstructure at different length scales. Each layer has specific mechanical and structural …

A viscoelastic constitutive model for human femoropopliteal arteries

W Zhang, M Jadidi, SA Razian, GA Holzapfel… - Acta biomaterialia, 2023 - Elsevier
High failure rates present challenges for surgical and interventional therapies for peripheral
artery disease of the femoropopliteal artery (FPA). The FPA's demanding biomechanical …

[HTML][HTML] Multiscale computational modeling of arterial micromechanics: A review

M Dalbosco, EA Fancello, GA Holzapfel - Computer Methods in Applied …, 2024 - Elsevier
The mechanical properties of arterial tissue play a central role in healthy human physiology
and have therefore been extensively studied and modeled in recent decades. These …

[HTML][HTML] Single-cell profiling reveals inflammatory polarization of human carotid versus femoral plaque leukocytes

J Slysz, A Sinha, M DeBerge, S Singh, H Avgousti… - JCI insight, 2023 - ncbi.nlm.nih.gov
Femoral atherosclerotic plaques are less inflammatory than carotid plaques histologically,
but limited cell-level data exist regarding comparative immune landscapes and polarization …

Calcification prevalence in different vascular zones and its association with demographics, risk factors, and morphometry

M Jadidi, W Poulson, P Aylward… - American Journal …, 2021 - journals.physiology.org
Vascular calcification is associated with a higher incidence of cardiovascular events, but its
prevalence in different vascular zones and the influence of demographics, risk factors, and …

Effects of age, elastin density, and glycosaminoglycan accumulation on the delamination strength of human thoracic and abdominal aortas

R Shahbad, A Kamenskiy, SA Razian, M Jadidi… - Acta Biomaterialia, 2024 - Elsevier
Aortic dissection is a life-threatening condition caused by layer separation. Despite
extensive research, the relationship between the aortic wall's structural integrity and …

Mechanical, structural, and physiologic differences between above and below-knee human arteries

P Struczewska, SA Razian, K Townsend, M Jadidi… - Acta Biomaterialia, 2024 - Elsevier
Abstract Peripheral Artery Disease (PAD) affects the lower extremities and frequently results
in poor clinical outcomes, especially in the vessels below the knee. Understanding the …

Lengthwise regional mechanics of the human aneurysmal ascending thoracic aorta

SA Tarraf, B Kramer, E Vianna, C Gillespie, E Germano… - Acta biomaterialia, 2023 - Elsevier
The prognosis of patients undergoing emergency endovascular repair of ascending thoracic
aortic aneurysm (ATAA) depends on defect location, with root disease bearing worse …