Is South Africa being spared the global opioid crisis? A review of trends in drug treatment demand for heroin, nyaope and codeine-related medicines in South Africa …

N Harker, WC Lucas, R Laubscher, S Dada… - International Journal of …, 2020 - Elsevier
Abstract Introduction South Africa has seen a sharp increase in treatment admission trends
for opioids despite beliefs that rates of opioid use remain low and do not represent a major …

Desorption atmospheric pressure chemical ionization: A review

CN Pitman, WR LaCourse - Analytica Chimica Acta, 2020 - Elsevier
Abstract Desorption Atmospheric Pressure Chemical Ionization (DAPCI) is an ambient
ionization technique for mass spectrometry (MS). DAPCI is a plasma-based ionization …

[HTML][HTML] Chemical profiling of the street cocktail drug 'nyaope'in South Africa using GC–MS I: Stability studies of components of 'nyaope'in organic solvents

PM Mthembi, EM Mwenesongole, MD Cole - Forensic science international, 2018 - Elsevier
Nyaope, a street drug commonly found in South Africa, is a mixture of low grade heroin,
cannabis products, antiretroviral drugs and other materials added as cutting agents. It is a …

Removal of antiretroviral drugs stavudine and zidovudine in water under UV254 and UV254/H2O2 processes: Quantum yields, kinetics and ecotoxicology assessment

D Russo, A Siciliano, M Guida, R Andreozzi… - Journal of hazardous …, 2018 - Elsevier
The concentration of antiretroviral drugs in wastewater treatment plants (WWTP) effluents
and surface waters of many countries has increased significantly due to their widespread …

High retention in an opioid agonist therapy project in Durban, South Africa: the role of best practice and social cohesion

M Marks, A Scheibe, S Shelly - Harm reduction journal, 2020 - Springer
Background Moral conservatism within government and communities has resulted in a
reluctance to support the provision of opioid agonist therapy for people with opioid use …

COVID-19 restrictions and increased risk of overdose for street-based people with opioid dependence in South Africa

MJ Stowe, A Scheibe, S Shelly, M Marks - SAMJ: South African …, 2020 - scielo.org.za
To the Editor: The placement of street-based people in temporary shelters as part of South
Africa (SA)'s lockdown efforts to mitigate the COVID-19 epidemic increases the risk of …

Developing an advocacy agenda for increasing access to opioid substitution therapy as part of comprehensive services for people who use drugs in South Africa

A Scheibe, M Marks, S Shelly, T Gerardy… - South African Medical …, 2018 - journals.co.za
Opioid use disorders, including heroin use disorders, account for 70% of the global burden
of drug-related disease [1] and disproportionately affect people who have unmet social …

[HTML][HTML] Chemical profiling of the street cocktail drug 'nyaope'in South Africa using GC–MS II: Stability studies of the cannabinoid, opiate and antiretroviral components …

PM Mthembi, EM Mwenesongole, MD Cole - Forensic science international, 2019 - Elsevier
Nyaope is a mixture of low grade heroin, cannabis products, antiretroviral drugs and other
materials added as bulking agents. It is a highly physically additive mixture which is smoked …

[HTML][HTML] The Cytotoxic Effects of Nyaope, a Heroin-based Street Drug, in SH-SY5Y Neuroblastoma Cells

WMU Daniels, MM Sekhotha, N Morgan… - IBRO Neuroscience …, 2024 - Elsevier
Nyaope is a local adulterated drug that contributes significantly to the psychosocial
challenge of substance use in South Africa. Despite being a huge burden on society and the …

[PDF][PDF] Southern African HIV Clinicians Society guidelines for harm reduction

A Scheibe, G Sibeko, S Shelly, T Rossouw… - Southern African journal …, 2020 - ajol.info
Executive summary We support public-health-focused interventions, as opposed to recovery-
focused interventions We support the decriminalisation of drug use as much as we oppose …