Dietary restriction (DR) decreases body weight, improves health, and extends lifespan. DR can be achieved by controlling how much and/or when food is provided, as well as by …
The circadian system orchestrates metabolism in daily 24-hour cycles. Such rhythms organize metabolism by temporally separating opposing metabolic processes and by …
The circadian clock, a highly specialized, hierarchical network of biological pacemakers, directs and maintains proper rhythms in endocrine and metabolic pathways required for …
Circadian rhythms and cellular metabolism are intimately linked. Here, we reveal that a high- fat diet (HFD) generates a profound reorganization of specific metabolic pathways, leading …
SK Davies, JE Ang, VL Revell… - Proceedings of the …, 2014 - National Acad Sciences
Sleep restriction and circadian clock disruption are associated with metabolic disorders such as obesity, insulin resistance, and diabetes. The metabolic pathways involved in human …
N Wittenbrink, B Ananthasubramaniam… - The Journal of …, 2018 - Am Soc Clin Investig
BACKGROUND. The circadian clock is a fundamental and pervasive biological program that coordinates 24-hour rhythms in physiology, metabolism, and behavior, and it is essential to …
Mitochondrial fission-fusion dynamics and mitochondrial bioenergetics, including oxidative phosphorylation and generation of ATP, are strongly clock controlled. Here we show that …
Insufficient sleep and circadian rhythm disruption are associated with negative health outcomes, including obesity, cardiovascular disease, and cognitive impairment, but the …
S Almoosawi, S Vingeliene, F Gachon, T Voortman… - Advances in …, 2019 - Elsevier
Chrono-nutrition is an emerging research field in nutritional epidemiology that encompasses 3 dimensions of eating behavior: timing, frequency, and regularity. To date, few studies have …