Neuroinflammation is a multifaceted physiological and pathophysiological response of the
brain to injury and disease. Given imaging findings of 18 kDa translocator protein (TSPO) …

Men and women exhibit differences in the development and progression of Alzheimer's
disease (AD). The factors underlying the sex differences in AD are not well understood. This …

Microglial phagocytosis is an energetically demanding process that plays a critical role in
the removal of toxic protein aggregates in Alzheimer's disease (AD). Recent evidence …

Background Depression is a heterogeneous disorder, with the exact neuronal mechanisms
causing the disease yet to be discovered. Recent work suggests it is accompanied by neuro …

The 18kDa Translocator Protein (TSPO) is the most commonly used tissue-specific marker of
inflammation in positron emission tomography (PET) studies. It is expressed in myeloid cells …

Abstract Introduction Genetic loci for Alzheimer's disease (AD) have been identified in whites
of European ancestry, but the genetic architecture of AD among other populations is less …

The evolutionarily conserved peripheral benzodiazepine receptor (PBR), or 18-kDa
translocator protein (TSPO), is thought to be essential for cholesterol transport and …

The 18 kDa translocator protein (TSPO), previously known as the peripheral
benzodiazepine receptor, is expressed in the injured brain. It has become known as an …

The 18-kilodalton translocator protein TSPO is found in mitochondrial membranes and
mediates the import of cholesterol and porphyrins into mitochondria. In line with the role of …

The translocator protein (TSPO) is an outer mitochondrial membrane protein that is widely
used as a biomarker of neuroinflammation, being markedly upregulated in activated …