A new clinical classification of acute myocardial infarction

B Lindahl, NL Mills - Nature Medicine, 2023 - nature.com
The existence of a universal definition of myocardial infarction—which involves classification
into multiple subtypes—has promoted the use of standard diagnostic criteria across the …

Exercise-induced cardiac troponin elevations: from underlying mechanisms to clinical relevance

VL Aengevaeren, AL Baggish, EH Chung, K George… - Circulation, 2021 - Am Heart Assoc
Serological assessment of cardiac troponins (cTn) is the gold standard to assess myocardial
injury in clinical practice. A greater magnitude of acutely or chronically elevated cTn …

Machine learning for diagnosis of myocardial infarction using cardiac troponin concentrations

D Doudesis, KK Lee, J Boeddinghaus, A Bularga… - Nature Medicine, 2023 - nature.com
Although guidelines recommend fixed cardiac troponin thresholds for the diagnosis of
myocardial infarction, troponin concentrations are influenced by age, sex, comorbidities and …

Prognostically relevant periprocedural myocardial injury and infarction associated with percutaneous coronary interventions: a Consensus Document of the ESC …

H Bulluck, V Paradies, E Barbato… - European heart …, 2021 - academic.oup.com
A substantial number of chronic coronary syndrome (CCS) patients undergoing
percutaneous coronary intervention (PCI) experience periprocedural myocardial injury or …

Cardiomuscular biomarkers in the diagnosis and prognostication of immune checkpoint inhibitor myocarditis

LH Lehmann, MB Heckmann, G Bailly, D Finke… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Immune checkpoint inhibitors (ICIs) are approved for multiple cancers but
can result in ICI-associated myocarditis, an infrequent but life-threatening condition …

High-sensitivity troponins and mortality in the general population

JW McEvoy, N Daya, O Tang, M Fang… - European heart …, 2023 - academic.oup.com
Aims Cardiac troponin T and I can be measured using a number of high-sensitivity (hs)
assays. This study aimed to characterize correlations between four such assays and test …

Percutaneous intracoronary delivery of plasma extracellular vesicles protects the myocardium against ischemia-reperfusion injury in Canis

H Wang, R Maimaitiaili, J Yao, Y Xie, S Qiang, F Hu… - …, 2021 - Am Heart Assoc
Plasma circulating extracellular vesicles (EVs) have been utilized as a potential therapeutic
strategy to treat ischemic disease through intramyocardial injection (efficient but invasive) or …

Cardiac troponin release following coronary artery bypass grafting: mechanisms and clinical implications

S Heuts, C Gollmann-Tepeköylü… - European Heart …, 2023 - academic.oup.com
The use of biomarkers is undisputed in the diagnosis of primary myocardial infarction (MI),
but their value for identifying MI is less well studied in the postoperative phase following …

Single Troponin Measurement to Rule Out Myocardial Infarction: JACC Review Topic of the Week

AS Jaffe, R Body, NL Mills, KM Aakre… - Journal of the American …, 2023 - jacc.org
The term “single-sample rule-out” refers to the ability of very low concentrations of high-
sensitivity cardiac troponin (hs-cTn) on presentation to exclude acute myocardial infarction …

Three-biomarker joint strategy for early and accurate diagnosis of acute myocardial infarction via a multiplex electrochemiluminescence immunoarray coupled with …

M Guo, D Du, J Wang, Y Ma, D Yang… - … & Biomedical Imaging, 2023 - ACS Publications
Acute myocardial infarction (AMI) represents a leading cause of death globally. Key to AMI
recovery is timely diagnosis and initiation of treatment, ideally within 3 h of symptom onset …