Iron is an essential trace metal for almost all organisms, including human; however,
oxidative stress can easily be caused when iron is in excess, producing toxicity to the human …

Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …

Importance Network hyperexcitability may contribute to cognitive dysfunction in patients with
Alzheimer disease (AD). Objective To determine the ability of the antiseizure drug …

Sleep monitoring may provide markers for future Alzheimer's disease; however, the
relationship between sleep and cognitive function in preclinical and early symptomatic …

Background: Neuronal-and circuit-level abnormalities of excitation and inhibition are shown
to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer's disease …

While shaped and constrained by axonal connections, fMRI-based functional connectivity
reorganizes in response to varying interareal input or pathological perturbations. However …

Identifying effective treatments for Alzheimer's disease (AD) has proven challenging and has
instigated a shift in AD research focus toward the earliest disease-initiating cellular …

People with Alzheimer's disease (AD) have significantly higher rates of subclinical and overt
epileptiform activity. In animal models, oligomeric Aβ amyloid is able to induce neuronal …

Every year the Alzheimer's Association publishes a report that provides facts and figures
indicating the public health, social and economic impact of Alzheimer's disease (AD). In …

Background The mechanism of synaptic loss in Alzheimer's disease is poorly understood
and may be associated with tau pathology. In this combined positron emission tomography …