Controlling gene expression in response to stress

E De Nadal, G Ammerer, F Posas - Nature Reviews Genetics, 2011 - nature.com
Acute stress puts cells at risk, and rapid adaptation is crucial for maximizing cell survival.
Cellular adaptation mechanisms include modification of certain aspects of cell physiology …

Osmotic stress signaling and osmoadaptation in yeasts

S Hohmann - Microbiology and molecular biology reviews, 2002 - Am Soc Microbiol
The ability to adapt to altered availability of free water is a fundamental property of living
cells. The principles underlying osmoadaptation are well conserved. The yeast …

Response to hyperosmotic stress

H Saito, F Posas - Genetics, 2012 - academic.oup.com
An appropriate response and adaptation to hyperosmolarity, ie., an external osmolarity that
is higher than the physiological range, can be a matter of life or death for all cells. It is …

[HTML][HTML] Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae

RE Chen, J Thorner - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2007 - Elsevier
Signaling pathways that activate different mitogen-activated protein kinases (MAPKs) elicit
many of the responses that are evoked in cells by changes in certain environmental …

The Cryptococcus neoformans capsule: a sword and a shield

TR O'Meara, JA Alspaugh - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …

How Saccharomyces Responds to Nutrients

S Zaman, SI Lippman, X Zhao… - Annual review of …, 2008 - annualreviews.org
Yeast cells sense the amount and quality of external nutrients through multiple
interconnected signaling networks, which allow them to adjust their metabolism …

The HOG pathway and the regulation of osmoadaptive responses in yeast

E de Nadal, F Posas - FEMS yeast research, 2022 - academic.oup.com
Cells coordinate intracellular activities in response to changes in the extracellular
environment to maximize their probability of survival and proliferation. Eukaryotic cells need …

Inducible gene expression: diverse regulatory mechanisms

VM Weake, JL Workman - Nature Reviews Genetics, 2010 - nature.com
The rapid activation of gene expression in response to stimuli occurs largely through the
regulation of RNA polymerase II-dependent transcription. In this Review, we discuss events …

Role of the Hog1 Stress-activated Protein Kinase in the Global Transcriptional Response to Stress in the Fungal Pathogen Candida albicans

B Enjalbert, DA Smith, MJ Cornell, I Alam… - Molecular biology of …, 2006 - Am Soc Cell Biol
The resistance of Candida albicans to many stresses is dependent on the stress-activated
protein kinase (SAPK) Hog1. Hence we have explored the role of Hog1 in the regulation of …

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

D Sanglard, A Coste, S Ferrari - FEMS yeast research, 2009 - academic.oup.com
Fungi are primitive eukaryotes and have adapted to a variety of niches during evolution.
Some fungal species may interact with other life forms (plants, insects, mammals), but are …