Gut microbiome and microbial metabolites in NAFLD and after bariatric surgery: Correlation and causality

Y Xia, M Ren, J Yang, C Cai, W Cheng… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is currently related to a heavy socioeconomic
burden and increased incidence. Since obesity is the most prevalent risk factor for NAFLD …

Unlocking liver health: Can tackling myosteatosis spark remission in metabolic dysfunction‐associated steatotic liver disease?

G Henin, A Loumaye, L Deldicque… - Liver …, 2024 - Wiley Online Library
Myosteatosis is highly prevalent in metabolic dysfunction‐associated steatotic liver disease
(MASLD) and could reciprocally impact liver function. Decreasing muscle fat could be …

[HTML][HTML] Incretin hormones, obesity and gut microbiota

G Angelini, S Russo, G Mingrone - Peptides, 2024 - Elsevier
Over the past 40 years, the prevalence of obesity has risen dramatically, reaching epidemic
proportions. By 2030 the number of people affected by obesity will reach 1.12 billion …

[HTML][HTML] Improvement of Metabolic-Associated Fatty Liver Disease by Magnetic Resonance Spectroscopy in Morbidly Obese Women Undergoing Roux-en-Y Gastric …

J Ruiz-Tovar, C Llavero, M Rodriguez-Ortega… - Nutrients, 2024 - mdpi.com
(1) Background: Bariatric surgery has demonstrated the capacity to improve metabolic-
associated fatty liver disease (MAFLD) in patients with morbid obesity. In addition, the …

Physiology Reconfigured: How Does Bariatric Surgery Lead to Diabetes Remission?

VL Albaugh, C Axelrod, KP Belmont… - Endocrinology and …, 2023 - endo.theclinics.com
Type 2 diabetes affects more than 450 million people worldwide 1 and is a leading cause of
death due to increased risk of cardiovascular, liver, and kidney disease, as well as …

Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis

G Angelini, L Castagneto-Gissey, S Salinari… - Nature …, 2022 - nature.com
A high-fat diet increases the risk of insulin resistance, type-2 diabetes, and non-alcoholic
steato-hepatitis. Here we identified two heat-shock proteins, Heat-Shock-Protein70 and …

[HTML][HTML] Intestinal heat shock proteins in metabolic syndrome: Novel mediators of obesity and its comorbidities resolution after metabolic surgery

G Angelini, S Russo, G Mingrone - Cell Stress and Chaperones, 2024 - Elsevier
Over the past 40 years, the prevalence of obesity has risen dramatically, reaching epidemic
proportions. Metabolic surgery has proven to be highly effective in treating obesity, leading …

Association between Dietary Pattern, Nutritional Status, Metabolic Factors, and Nonalcoholic Fatty Liver Disease

G Xing, Y Huang, X Liu - Contrast Media & Molecular Imaging, 2022 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) can be harmful to the body to varying degrees, and
over a prolonged period, patients may develop steatotic cirrhosis or even develop liver …

The role of gut microbiota in duodenal-jejunal bypass surgery-induced improvement of hepatic steatosis in hfd-fed rats

Y Gao, J Zhang, X Xiao, Y Ren, X Yan, J Yue… - Frontiers in Cellular …, 2021 - frontiersin.org
Bariatric surgery including duodenal-jejunal bypass surgery (DJB) improves insulin
sensitivity and reduces obesity-associated inflammation. However, the underlying …

A gut-centric model of metabolic homeostasis

H Rajagopalan, JC Lopez-Talavera… - Journal of Diabetes …, 2022 - journals.sagepub.com
Modern changes in diet and lifestyle have led to an explosion of insulin resistance and
metabolic diseases around the globe which, if left unchecked, will become a principal driver …