The design and construction of synthetic cells–human‐made microcompartments that mimic
features of living cells–have experienced a real boom in the past decade. While many efforts …

Interest in peptide‐based supramolecular materials has grown extensively since the 1980s
and the application of computational methods has paralleled this. These methods contribute …

Liquid–liquid phase separation (LLPS) is an emerging phenomenon in cell physiology and
diseases. The weak multivalent interaction prerequisite for LLPS is believed to be facilitated …

Disease-associated progression of protein dysfunction is typically determined by an
interplay of transition pathways leading to liquid–liquid phase separation (LLPS) and …

As in natural cytoskeletons, the cooperative assembly of fibrillar networks can be hosted
inside compartments to engineer biomimetic functions, such as mechanical actuation …

Therapeutic peptides are a major class of pharmaceutical drugs owing to their target‐
binding specificity as well as their versatility in inhibiting aberrant protein‐protein …

Coacervates, which are formed by liquid–liquid phase separation, have been extensively
explored as models for synthetic cells and membraneless organelles, so their in-depth …

Although post-translational lipidation is prevalent in eukaryotes, its impact on the liquid–
liquid phase separation of disordered proteins is still poorly understood. Here, we examined …

Utilizing biocondensates as feedstocks can be a state-of-the-art strategy for emulating
natural silk spinning. Although current biocondensates can form solid fibers using a …

Amyloid-β [Aβ (1–40)] aggregation into a fibrillar network is one of the major hallmarks of
Alzheimer's disease (AD). Recently, a few studies reported that polyphosphate (polyP), an …