Lung cancer is a common malignant tumor that occurs in the human body and poses a
serious threat to human health and quality of life. The existing treatment methods mainly …

Ferroptosis is a new type of regulatory cell death that differs from autophagy, apoptosis,
necrosis, and pyroptosis; it is caused primarily by the accumulation of iron and lipid …

Using whole-genome microarray data sets of the Immunological Genome Project, we
demonstrate a closer transcriptional relationship between NK cells and T cells than between …

Natural killer (NK) cells are the major lymphocyte subset of the innate immune system. Their
ability to mediate anti-tumor cytotoxicity and produce cytokines is well-established. However …

Abstract Serine Threonine Tyrosine Kinase 1 (STYK1) presents oncogenic properties in
many studies, and emerging evidence suggests that ferroptosis serve as a novel tumor …

Receptor tyrosine kinases (RTKs) play important roles in cell growth, motility, differentiation,
and survival. These single-pass membrane proteins are grouped into subfamilies based on …

Natural killer cells belong to the family of innate lymphoid cells comprising the frontline
defense against infected and transformed cells. Development and activation of natural killer …

Growth hormone receptor (GHR) has been demonstrated to be nuclear localized both in vivo
and in vitro, but the significance of this observation has remained elusive. Here we show that …

Nrf2-small Maf heterodimer activates the transcription of many cytoprotective genes through
the antioxidant response element and serves as a key factor in xenobiotic and oxidative …

LKB1 is a tumor susceptibility gene for the Peutz–Jeghers cancer syndrome and is a target
for mutational inactivation in sporadic human malignancies. LKB1 encodes a …