Background Severe sepsis and septic shock remain significant public health concerns.
Appropriate emergency department management includes early recognition, hemodynamic …

Background: Administering antimicrobial agents before obtaining blood cultures could
potentially decrease time to treatment and improve outcomes, but it is unclear how this …

Introduction Bloodstream infections are associated with high mortality rates and contribute
substantially to healthcare costs, but a consensus on the prognostic benefits of appropriate …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF
MS) for the identification of bacteria and fungi was recently introduced in microbiology …

Background Early administration of appropriate antimicrobials has been correlated with a
better prognosis in patients with bacteremia, but the optimum timing of early antibiotic …

Early appropriate antimicrobial therapy is crucial in patients with sepsis and septic shock.
Studies often focus on time to first dose of appropriate antibiotics, but subsequent dosing is …

Rising antibiotic resistance amidst indiscriminate antibiotic use is a growing public health
concern. Efforts to curb this trend have had limited success, particularly in developing …

Antimicrobial stewardship (AS) programs are effective in improving clinical outcomes
associated with antimicrobial therapies while improving patient safety by reducing adverse …

Background Rapid detection, early resuscitation, and appropriate antibiotic use are crucial
for sepsis care. Accurate identification of the site of infection may facilitate a timely provision …

Objective Few studies have sought to establish how often death after sepsis is related to the
sepsis and how often underlying diseases have a major role in case fatality. Methods In this …