Cellular and molecular pathophysiology of traumatic brain injury: what have we learned so far?

MAM Freire, GS Rocha, LO Bittencourt, D Falcao… - Biology, 2023 - mdpi.com
Simple Summary Traumatic brain injury (TBI) is a catastrophic event to the health and life of
its sufferers, and it also affects their relatives. In addition to the underlying complications of …

Executive (dys) function after traumatic brain injury: special considerations for behavioral pharmacology

JE Ozga, JM Povroznik… - Behavioural …, 2018 - journals.lww.com
Executive function is an umbrella term that includes cognitive processes such as decision-
making, impulse control, attention, behavioral flexibility, and working memory. Each of these …

Cannabidiol's neuroprotective properties and potential treatment of traumatic brain injuries

MM Aychman, DL Goldman, JS Kaplan - Frontiers in neurology, 2023 - frontiersin.org
Cannabidiol (CBD) has numerous pharmacological targets that initiate anti-inflammatory,
antioxidative, and antiepileptic properties. These neuroprotective benefits have generated …

Neurotransmitter changes after traumatic brain injury: an update for new treatment strategies

JL McGuire, LB Ngwenya, RE McCullumsmith - Molecular Psychiatry, 2019 - nature.com
Traumatic brain injury (TBI) is a pervasive problem in the United States and worldwide, as
the number of diagnosed individuals is increasing yearly and there are no efficacious …

Senescence-associated-β-galactosidase staining following traumatic brain injury in the mouse cerebrum

T Tominaga, R Shimada, Y Okada, T Kawamata… - PLoS …, 2019 - journals.plos.org
Primary and secondary traumatic brain injury (TBI) can cause tissue damage by inducing
cell death pathways including apoptosis, necroptosis, and autophagy. However, similar …

Making migraine easier to stomach: the role of the gut− brain− immune axis in headache disorders

M Sgro, J Ray, E Foster… - European Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Headache disorders place a significant burden on the
healthcare system, being the leading cause of disability in those under 50 years. Novel …

[HTML][HTML] Restoring consciousness with pharmacologic therapy: Mechanisms, targets, and future directions

ME Barra, K Solt, X Yu, BL Edlow - Neurotherapeutics, 2024 - Elsevier
Severe brain injury impairs consciousness by disrupting a broad spectrum of
neurotransmitter systems. Emerging evidence suggests that pharmacologic modulation of …

[HTML][HTML] What happens in TBI? A wide talk on animal models and future perspective

S Kundu, S Singh - Current neuropharmacology, 2023 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is a global healthcare concern and a leading cause of death.
The most common causes of TBI include road accidents, sports injuries, violence in …

Gene expression in meningeal lymphatic endothelial cells following traumatic brain injury in mice

R Shimada, Y Tatara, K Kibayashi - PLoS One, 2022 - journals.plos.org
Meningeal lymphatic vessels transport both the cerebrospinal fluid and interstitial fluid to the
deep cervical lymph nodes. Traumatic brain injury (TBI) is accompanied by meningeal …

Comprehensive topographical map of the serotonergic fibers in the male mouse brain

JR Awasthi, K Tamada, ETN Overton… - Journal of …, 2021 - Wiley Online Library
It is well established that serotonergic fibers distribute throughout the brain. Abnormal
densities or patterns of serotonergic fibers have been implicated in neuropsychiatric …