Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Astrocytes, a major type of glial cell, are known to play key supportive roles in brain function,
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …

Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

Preeclampsia is a dangerous hypertensive disorder of pregnancy with known links to
negative child health outcomes. Here, we review epidemiological and basic neuroscience …

Abstract Down's syndrome (DS), caused by trisomy of human chromosome 21, is the most
common genetic cause of intellectual disability. Here we use induced pluripotent stem cells …

Based on the diverse physiological influence, the impact of glial cells has become much
more evident on neurological illnesses, resulting in the origins of many diseases appearing …

Beyond its importance in sustaining or modulating different aspects of the activity of the
central nervous system (CNS), the cholinergic system plays important roles during …

Alcohol consumption during pregnancy can produce a variety of central nervous system
(CNS) abnormalities in the offspring resulting in a broad spectrum of cognitive and …

Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes
enwrap the neuronal components of the tripartite synapse, and due to this close interaction …

Astrocytes are now distinguished as major regulators of neuronal growth and synaptic
development. Recently, they have been identified as key players in the progression of a …