Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

The colonic epithelium has both absorptive and secretory functions. The transport is
characterized by a net absorption of NaCl, short-chain fatty acids (SCFA), and water …

▪ Abstract Successful viral replication requires not only the efficient production and spread of
progeny, but also evasion of host defense mechanisms that limit replication by killing …

Viroporins are indispensable for viral replication. As intracellular ion channels they disturb
pH gradients of organelles and allow Ca 2+ flux across ER membranes. Viroporins interact …

Viroporins are a group of proteins that participate in several viral functions, including the
promotion of release of viral particles from cells. These proteins also affect cellular functions …

The channel-forming activity of a family of small, hydrophobic integral membrane proteins
termed 'viroporins' is essential to the life cycles of an increasingly diverse range of RNA and …

Virus infections can result in a range of cellular injuries and commonly this involves both the
plasma and intracellular membranes, resulting in enhanced permeability. Viroporins are a …

We previously identified the function of the hepatitis C virus (HCV) p7 protein as an ion
channel in artificial lipid bilayers and demonstrated that this in vitro activity is inhibited by …

Many viruses alter intracellular calcium homeostasis. The rotavirus nonstructural protein 4
(NSP4), an endoplasmic reticulum (ER) transmembrane glycoprotein, increases intracellular …

Infectious bursal disease virus (IBDV) encodes a 17-kDa nonstructural polypeptide known
as VP5. This polypeptide is not essential for virus replication in vitro but it plays an important …