Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

The chitinolytic machinery of S erratia marcescens is one of the best known enzyme systems
for the conversion of insoluble polysaccharides. This machinery includes four chitin‐active …

Mucinolytic bacteria modulate host–microbiota symbiosis and dysbiosis through their ability
to degrade mucin O-glycans. However, how and to what extent bacterial enzymes are …

Hen egg-white lysozyme (HEWL) was the first enzyme to have its three-dimensional
structure determined by X-ray diffraction techniques. A catalytic mechanism, featuring a long …

When cultured in broth, fresh clinical isolates of the gram-negative periodontal pathogen
Actinobacillus actinomycetemcomitans form tenaciously adherent biofilm colonies on …

The past year has witnessed the expected increase in the number of solved structures of
glycoside hydrolases and glycosyltransferases, and their constitutive modules. These …

The three-dimensional structure of glycosidases and of their complexes and the study of
transition-state mimics reveal structural details that correlate with mechanism. Of particular …

Abstract Background Chitinases (EC. 3.2. 1.14) hydrolyze the β-1, 4-linkages in chitin, an
abundant N-acetyl-β-D-glucosamine polysaccharide that is a structural component of …

The intense arms race between bacteria and phages has led to the development of diverse
antiphage defense systems in bacteria. Unlike well-known restriction-modification and …

The post-translational modification of serine and threonine residues ofnucleocytoplasmic
proteins with 2-acetamido-2-deoxy-d-glucopyranose (GlcNAc) is a reversible process …