Primary immune thrombocytopenia: novel insights into pathophysiology and disease management

A Singh, G Uzun, T Bakchoul - Journal of Clinical Medicine, 2021 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune disorder defined by a significantly
reduced number of platelets in blood circulation. Due to low levels of platelets, ITP is …

Management of adult patients with immune thrombocytopenia (ITP): a review on current guidance and experience from clinical practice

F Song, H Al-Samkari - Journal of Blood Medicine, 2021 - Taylor & Francis
Immune thrombocytopenia (ITP) is an autoimmune process resulting in increased
destruction and inadequate production of platelets that can result in bleeding, fatigue, and …

[HTML][HTML] Recent advances in treatments of adult immune thrombocytopenia

DS Kim - Blood research, 2022 - synapse.koreamed.org
Immune thrombocytopenia (ITP) is isolated thrombocytopenia characterized by autoimmune-
mediated disruption of platelet without other etiologies. Treatments for chronic ITP consist of …

Self-Administration of Burosumab in Children and Adults with X-Linked Hypophosphataemia in Two Open-Label, Single-Arm Clinical Studies

T Kubota, N Namba, H Tanaka, K Muroya… - Advances in …, 2023 - Springer
Introduction X-linked hypophosphataemia (XLH) is a rare, genetic renal phosphate-wasting
disease, resulting from excess fibroblast growth factor 23 (FGF23) activity, which has a …

[HTML][HTML] The treatment of immune thrombocytopenia (ITP)—focus on thrombopoietin receptor agonists

DJ Kuter - Annals of Blood, 2021 - aob.amegroups.org
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by increased
platelet destruction along with reduced platelet production. All treatments attempt either to …

Developments in the production of platelets from stem cells

J Yang, J Luan, Y Shen, B Chen - Molecular Medicine …, 2021 - spandidos-publications.com
Platelets are small pieces of cytoplasm that have become detached from the cytoplasm of
mature megakaryocytes (MKs) in the bone marrow. Platelets modulate vascular system …

[HTML][HTML] Clinical overview and practical considerations for optimizing romiplostim therapy in patients with immune thrombocytopenia

DJ Kuter, MD Tarantino, T Lawrence - Blood Reviews, 2021 - Elsevier
The fundamental treatment goal for patients with immune thrombocytopenia (ITP) is reduced
or ameliorated bleeding. Although various treatment options exist for the management of …

Immune thrombocytopenia management during COVID‐19 pandemic: An Italian monocentric experience

G Lapietra, A Ferretti, E Baldacci, A Chistolini… - …, 2022 - Wiley Online Library
Over the last 2 years, different cases of immune thrombocytopenia (ITP) in patients affected
by SARS‐CoV2 have been reported. The management of SARS‐CoV2 in subjects with …

Evaluating unmet needs in large-volume subcutaneous drug delivery: US payer perspectives on a novel, large-volume on-body delivery system

M Desai, J Kenney, E Pezalla - Current Medical Research and …, 2024 - Taylor & Francis
Objective Existing healthcare systems face finite resource allocation and budgetary
constraints, resulting in a substantial need for innovative solutions to enhance service …

Experts' review: the emerging roles of romiplostim in immune thrombocytopenia (ITP)

F Chen, V McDonald, A Newland - Expert Opinion on Biological …, 2021 - Taylor & Francis
Introduction The management of ITP has in recent years been transformed from reliance on
immunosuppressants and splenectomy to targeted therapy with thrombopoietin receptor …