Towards a deeper understanding of the vaginal microbiota

M France, M Alizadeh, S Brown, B Ma, J Ravel - Nature microbiology, 2022 - nature.com
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

[HTML][HTML] The role of lactic acid production by probiotic Lactobacillus species in vaginal health

G Tachedjian, M Aldunate, CS Bradshaw… - Research in …, 2017 - Elsevier
Vaginal eubiosis is characterised by beneficial lactobacillus-dominated microbiota. In
contrast, vaginal dysbiosis (eg bacterial vaginosis, BV), characterised by an overgrowth of …

Lactobacilli dominance and vaginal pH: why is the human vaginal microbiome unique?

EA Miller, DAE Beasley, RR Dunn… - Frontiers in microbiology, 2016 - frontiersin.org
The human vaginal microbiome is dominated by bacteria from the genus Lactobacillus,
which create an acidic environment thought to protect women against sexually transmitted …

Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis

M Aldunate, D Srbinovski, AC Hearps… - Frontiers in …, 2015 - frontiersin.org
Lactic acid and short chain fatty acids (SCFAs) produced by vaginal microbiota have
reported antimicrobial and immune modulatory activities indicating their potential as …

Why do lactobacilli dominate the human vaginal microbiota?

SS Witkin, IM Linhares - BJOG: An International Journal of …, 2017 - Wiley Online Library
Lactobacilli are the most abundant vaginal bacteria in women. They inhibit binding of other
bacteria to epithelial cells and produce lactic acid that kills or inhibits the growth of many …

Current treatment of bacterial vaginosis—limitations and need for innovation

CS Bradshaw, JD Sobel - The Journal of infectious diseases, 2016 - academic.oup.com
Practitioners and patients alike widely recognize the limitations of current therapeutic
approaches to the treatment of bacterial vaginosis (BV). Options remain extremely limited …

The reproductive microbiome: an emerging driver of sexual selection, sexual conflict, mating systems, and reproductive isolation

M Rowe, L Veerus, P Trosvik, A Buckling… - Trends in ecology & …, 2020 - cell.com
All multicellular organisms host microbial communities in and on their bodies, and these
microbiomes can have major influences on host biology. Most research has focussed on the …

Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner

E Jašarević, CD Howard, AM Misic, DP Beiting… - Scientific Reports, 2017 - nature.com
The microbiome is a regulator of host immunity, metabolism, neurodevelopment, and
behavior. During early life, bacterial communities within maternal gut and vaginal …

Characterization of microbial communities in the chicken oviduct and the origin of chicken embryo gut microbiota

S Lee, TM La, HJ Lee, IS Choi, CS Song, SY Park… - Scientific reports, 2019 - nature.com
The transferred microbiota from mother to baby constitutes the initial infant gastrointestinal
microbiota and has an important influence on the development and health of infants in …

Antimicrobial peptides in the female reproductive tract: a critical component of the mucosal immune barrier with physiological and clinical implications

VL Yarbrough, S Winkle… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND At the interface of the external environment and the mucosal surface of the
female reproductive tract (FRT) lies a first-line defense against pathogen invasion that …