Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
still raging. However, the pathophysiology of acute and post-acute manifestations of COVID …
Understanding COVID-19-associated coagulopathy
EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …
[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …
and subjective components. They are common and debilitating, and can affect the ability to …
Chronic viral coinfections differentially affect the likelihood of developing long COVID
MJ Peluso, TM Deveau, SE Munter… - The Journal of …, 2023 - Am Soc Clin Investig
BACKGROUND The presence and reactivation of chronic viral infections, such as EBV,
CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but …
CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but …
Neurovascular injury with complement activation and inflammation in COVID-19
The underlying mechanisms by which severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) leads to acute and long-term neurological manifestations remains obscure …
(SARS-CoV-2) leads to acute and long-term neurological manifestations remains obscure …
Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
C Greene, R Connolly, D Brennan, A Laffan… - Nature …, 2024 - nature.com
Vascular disruption has been implicated in coronavirus disease 2019 (COVID-19)
pathogenesis and may predispose to the neurological sequelae associated with long …
pathogenesis and may predispose to the neurological sequelae associated with long …
The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2
L Bauer, BM Laksono, FMS de Vrij, SA Kushner… - Trends in …, 2022 - cell.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is associated with
a diverse spectrum of neurological complications during the acute and postacute stages …
a diverse spectrum of neurological complications during the acute and postacute stages …
Pathogenesis underlying neurological manifestations of long COVID syndrome and potential therapeutics
The development of long-term symptoms of coronavirus disease 2019 (COVID-19) more
than four weeks after primary infection, termed “long COVID” or post-acute sequela of …
than four weeks after primary infection, termed “long COVID” or post-acute sequela of …
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2
S Krasemann, U Haferkamp, S Pfefferle, MS Woo… - Stem cell reports, 2022 - cell.com
Neurological complications are common in COVID-19. Although SARS-CoV-2 has been
detected in patients' brain tissues, its entry routes and resulting consequences are not well …
detected in patients' brain tissues, its entry routes and resulting consequences are not well …