Rescuing or repairing neural tissues is of utmost importance to the patient's quality of life
after an injury. To remedy this, many novel biomaterials are being developed that are …

Early-life immune insults (ELII) including xenobiotic-induced developmental immunotoxicity
(DIT) are important factors in childhood and adult chronic diseases. However, prenatal and …

Cellular injury in AQP4-IgG seropositive neuromyelitis spectrum disorder (herein called
NMO) involves AQP4-IgG binding to astrocytes, resulting in astrocyte injury by complement …

Recent developments in digital light processing (DLP) can advance the structural and
biochemical complexity of perfusable in vitro models of the blood–brain barrier. Here, we …

Neurotrauma, a term referencing both traumatic brain and spinal cord injuries, is unique to
neurodegeneration in that onset is clearly defined. From the perspective of matrix …

Astrocytes, the most representative glial cells in the brain, play a multitude of crucial
functions for proper neuronal development and synaptic‐network formation, including …

An urgent need of more effective and personalized treatments for cancer and other genetic
diseases is becoming a generalized claim. This is pushing forward experimental alternative …

It is well known that cell surface immune receptors play a critical role in regulating immune
and inflammatory processes in the central nervous system (CNS). We have analyzed the …

Uncontrolled and chronic inflammatory states in the Central Nervous System (CNS) are the
hallmark of neurodegenerative pathology and every injury or stroke-related insult. The key …

The multifunctional protein osteopontin (OPN) is expressed in the substantia nigra (SN) and
protects nigral dopaminergic neurones against toxic insult in animal models of Parkinson's …