Parasitic diseases have a great impact in human and animal health. The gold standard for
the diagnosis of the majority of parasitic infections is still conventional microscopy, which …

Influenza is a zoonotic disease, infecting a wide variety of warm-blooded animals. It is
caused by an influenza virus, which has been found with hundreds of subtypes. These …

Malaria is among the major threats to global health with the main burden of disease being in
rural areas of developing countries where accurate diagnosis based on non-invasive …

Malaria poses a serious global health problem, with half the world population being at risk.
Regular screening is crucial for breaking the transmission cycle and combatting the disease …

Background: Eukaryotic topoisomerase 1 is a potential target of anti-parasitic and anti-
cancer drugs. Parasites require topoisomerase 1 activity for survival and, consequently …

Human DNA topoisomerase IB controls the topological state of supercoiled DNA through a
complex catalytic cycle that consists of cleavage and religation reactions, allowing the …

The main therapies of hepatocellular carcinoma (HCC) are hepatectomy and liver
transplantation, but the recurrence rate of HCC after radical resection remains high. We …

Rapid and reliable diagnosis is essential in the fight against malaria, which remains one of
the most deadly infectious diseases in the world. In the present study we take advantage of a …

The so-called Rolling Circle Amplification allows for amplification of circular DNA structures
in a manner that can be detected in real-time using nucleotide-based molecular beacons …

DNA nano-structures present appealing new means for monitoring different molecules.
Here, we demonstrate the assembly and utilization of a surface-attached double-stranded …