ABSTRACT Introduction: 1, 2, 3, 4-Tetrahydroisoquinoline (THIQ) is one of the 'privileged
scaffolds', commonly found in nature. Initially, this class of compounds was known for its …

Glioma is a brain tumor that arises from glial cells or glial progenitor cells, and represents
80% of malignant brain tumor incidence in the United States. Glioblastoma multiforme …

Currently, a lot of new chemical compounds are registered in the world, some of them are
used in various fields of medicine, pharmaceuticals or related fields. In this case, each of the …

Two bis (tetrahydroisoquinoline) derivatives of undecane were synthesized from brassylic
acid and 3, 4-dimethoxy-(or methylenedioxy-) phenylethylamine. It was shown that 4a and …

A row of 1-alkyne (C6-C17) derivatives against tetrahydroisoquinoline have been
synthesized. 1-alkyne (C6-C17) derivatives cytotoxicity against three lines of cancer cells …

The possible interaction of 6, 7-dimethoxy-1, 2, 3, 4-tetrahydroisoquinoline (heliamine) with
bicyclo [2.2. 1] hept-5-ene-endo-2, 3-dicarboxylic acid anhydride has been studied. Instead …

Aim: The aim of our research work is the synthesis of tetrahydroisoquinoline derivatives as
anti-Angiogenesis and anti-cancer agents. Background: Cancer is the second leading cause …

Glioma is a brain tumor that arises from glial cells or glial progenitor cells, and represents
80% of malignant brain tumor incidence in the United States. Glioblastoma multiforme …