Dexmedetomidine is an α 2-adrenoceptor agonist with sedative, anxiolytic, sympatholytic,
and analgesic-sparing effects, and minimal depression of respiratory function. It is potent …

Ischemia-reperfusion myocardial damage is a paradoxical tissue injury occurring during
percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) patients …

Background Intestinal ischemia/reperfusion (I/R) is a common clinical problem that occurs
during various clinical pathological processes. Dexmedetomidine (DEX), a widely used …

BACKGROUND: Myocardial infarction is a common perioperative complication, and blood
flow restoration causes ischemia/reperfusion injury (IRI). Dexmedetomidine (DEX) …

Background Endoplasmic reticulum stress (ERS)-mediated myocardial inflammation and
apoptosis plays an important role in myocardial ischemia/reperfusion (I/R) injury …

Dexmedetomidine (DEX) is a highly selective α2-adrenergic agonist with sedative and
analgesic properties, with minimal respiratory effects. It is used as a sedative in the intensive …

Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called
exosomes. Despite technical challenges in their purification and analysis, exosomes from …

Previous studies suggested a beneficial effect of natriuretic peptides in animal models of
cardiovascular disease, but the role of natriuretic peptide receptor C (NPRC) in the …

Myocardial ischemia‐reperfusion injury (MIRI) significantly worsens the outcomes of patients
with cardiovascular diseases. Dexmedetomidine (Dex) is recognized for its cardioprotective …

Background Myocardial ischemia/reperfusion (I/R) injury is a common cause of mortality.
Cardiac miR-146a is emerging as a potent regulator of myocardial function …