The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …
cluster and its members has been increasing steadily and the number of publications has …
Are innovation and new technologies in precision medicine paving a new era in patients centric care?
Healthcare is undergoing a transformation, and it is imperative to leverage new technologies
to generate new data and support the advent of precision medicine (PM). Recent scientific …
to generate new data and support the advent of precision medicine (PM). Recent scientific …
MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases
R Dai, SA Ahmed - Translational Research, 2011 - Elsevier
MicroRNAs (miRNAs) are newly discovered, small, noncoding ribonucleic acids (RNAs) that
play critical roles in the regulation of host genome expression at the posttranscriptional level …
play critical roles in the regulation of host genome expression at the posttranscriptional level …
The role of miRNA in inflammation and autoimmunity
RP Singh, I Massachi, S Manickavel, S Singh… - Autoimmunity …, 2013 - Elsevier
Abstract miRNAs are small non-coding RNA molecules that modulate the expression of
multiple protein-encoding genes at the post-transcriptional level. They have recently been …
multiple protein-encoding genes at the post-transcriptional level. They have recently been …
Circulating microRNAs as biomarkers for disease staging in multiple sclerosis
Objective MicroRNAs (miRNAs) are single‐stranded, small noncoding RNAs that regulate
gene expression. Because they are stable in serum, they are being developed as …
gene expression. Because they are stable in serum, they are being developed as …
Biomarkers in multiple sclerosis
Substantial effort has been made over the last six decades to identify biomarkers for multiple
sclerosis that can improve disease diagnosis, predict disease progression, and improve …
sclerosis that can improve disease diagnosis, predict disease progression, and improve …
The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
around the globe. Although it is twenty nucleotides long, it can modulate several gene …
MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …
neuronal and non-neuronal cell functions and play a key role in pathological conditions …
MicroRNA‐126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1
S Zhao, Y Wang, Y Liang, M Zhao, H Long… - Arthritis & …, 2011 - Wiley Online Library
Objective To identify microRNA genes with abnormal expression in the CD4+ T cells of
patients with systemic lupus erythematosus (SLE) and to determine the role of microRNA …
patients with systemic lupus erythematosus (SLE) and to determine the role of microRNA …
The emerging epigenetic role of CD8+ T cells in autoimmune diseases: a systematic review
Q Deng, Y Luo, C Chang, H Wu, Y Ding… - Frontiers in …, 2019 - frontiersin.org
Autoimmune diseases are usually complex and multifactorial, characterized by aberrant
production of autoreactive immune cells and/or autoantibodies against healthy cells and …
production of autoreactive immune cells and/or autoantibodies against healthy cells and …