The interaction of immunodeficiency viruses with dendritic cells

RM Steinman, A Granelli-Piperno, M Pope… - Dendritic Cells and Virus …, 2003 - Springer
Dendritic cells (DCs) can influence HIV-1 and SIV pathogenesis and protective mechanisms
at several levels. First, HIV-1 productively infects select populations of DCs in culture …

Current methods for loading dendritic cells with tumor antigen for the induction of antitumor immunity

Y Zhou, ML Bosch, ML Salgaller - Journal of immunotherapy, 2002 - journals.lww.com
The immunotherapy of cancer is predicated on the belief that it is possible to generate a
clinically meaningful antitumor response that provides patient benefit, such as improvement …

Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion

J Engelmayer, M Larsson, M Subklewe… - The Journal of …, 1999 - journals.aai.org
Vaccinia virus employs multiple mechanisms to evade the immune system, yet is highly
immunogenic. We studied the interaction between vaccinia and human dendritic cells (DCs) …

Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1

C Münz, KL Bickham, M Subklewe, ML Tsang… - The Journal of …, 2000 - rupress.org
The Epstein-Barr virus (EBV)-encoded nuclear antigen EBNA1 is critical for the persistence
of the viral episome in replicating EBV-transformed human B cells. Therefore, all EBV …

HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in …

D Weissman, H Ni, D Scales, A Dude… - The Journal of …, 2000 - journals.aai.org
Dendritic cells (DC) are the major APCs involved in naive T cell activation making them
prime targets of vaccine research. We observed that mRNA was efficiently transfected …

Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in …

A Gruber, J Kan-Mitchell, KL Kuhen… - Blood, The Journal …, 2000 - ashpublications.org
Dendritic cells (DCs) genetically modified to continually express and present antigens may
be potent physiologic adjuvants for induction of prophylactic or therapeutic immunity. We …

Lentivirus-transduced human monocyte-derived dendritic cells efficiently stimulate antigen-specific cytotoxic T lymphocytes

J Dyall, JB Latouche, S Schnell… - Blood, The Journal of …, 2001 - ashpublications.org
Dendritic cells (DCs) are professional antigen-presenting cells that are highly effective
adjuvants for immunizing against pathogens and tumor antigens. The potential merit of …

Poxvirus as a vector to transduce human dendritic cells for immunotherapy: abortive infection but reduced APC function

L Jenne, C Hauser, JF Arrighi, JH Saurat, AW Hügin - Gene therapy, 2000 - nature.com
Dendritic cells (DC) are potent antigen-presenting cells (APC). Ongoing preclinical and
clinical studies exploit this capacity for the immunotherapy of tumors. We tested vaccinia …

mRNA‐based Vaccines Targeting the T‐cell Epitope‐rich Domain of Epstein Barr Virus Latent Proteins Elicit Robust Anti‐Tumor Immunity in Mice

GX Zhao, GL Bu, GF Liu, XW Kong, C Sun… - Advanced …, 2023 - Wiley Online Library
Epstein‐Barr virus (EBV) is associated with various malignancies and infects> 90% of the
global population. EBV latent proteins are expressed in numerous EBV‐associated cancers …

Identification of an HLA-A*0201–restricted CD8+ T-cell epitope SSp-1 of SARS-CoV spike protein

B Wang, H Chen, X Jiang, M Zhang, T Wan, N Li… - Blood, 2004 - ashpublications.org
A novel coronavirus, severe acute respiratory syndrome (SARS)–associated coronavirus
(SARS-CoV), has been identified as the causal agent of SARS. Spike (S) protein is a major …