Zika virus neuropathogenesis: The different brain cells, host factors and mechanisms involved

TV Komarasamy, NAA Adnan, W James… - Frontiers in …, 2022 - frontiersin.org
Zika virus (ZIKV), despite being discovered six decades earlier, became a major health
concern only after an epidemic in French Polynesia and an increase in the number of …

[HTML][HTML] LYAR promotes colorectal cancer cell mobility by activating galectin-1 expression

Y Wu, M Liu, Z Li, XB Wu, Y Wang, Y Wang, M Nie… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.
However, the molecular mechanisms of CRC pathogenesis are not fully understood. In this …

The mechanism of zinc sulfate in improving fertility in obese rats analyzed by sperm proteomic analysis

J Ma, R Han, Y Li, T Cui, S Wang - BioMed Research …, 2020 - Wiley Online Library
This study investigates the mechanism underlying the improving effect of zinc on fertility in
obese rats using proteomics. The effects of three different doses of ZnSO4 on …

LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA

K Izumikawa, H Ishikawa, H Yoshikawa… - Nucleic Acids …, 2019 - academic.oup.com
Activation of ribosomal RNA (rRNA) synthesis is pivotal during cell growth and proliferation,
but its aberrant upregulation may promote tumorigenesis. Here, we demonstrate that the …

A Single-Cell Landscape of Spermioteleosis in Mice and Pigs

MM Liu, CQ Fan, GL Zhang - Cells, 2024 - mdpi.com
(1) Background: Spermatozoa acquired motility and matured in epididymis after production
in the testis. However, there is still limited understanding of the specific characteristics of …

Lyar, a cell growth-regulating zinc finger protein, was identified to be associated with cytoplasmic ribosomes in male germ and cancer cells

K Yonezawa, Y Sugihara, K Oshima, T Matsuda… - Molecular and cellular …, 2014 - Springer
Translational control is a basic mechanism for gene regulation in cells and important for
tissue growth and development in mammals. Deregulation of the mechanism thus causes …

[HTML][HTML] Identification and characterization of testis-specific gene expressions in mouse tissues

TM Alrubie, JP Shaik, AM Alamri, BO Almutairi… - Journal of King Saud …, 2023 - Elsevier
The growth and fertilization of germ cells require the identification and characterization of
their unique genes. Because the processes that take place in male germ cells are unique; …

Analysis of the role of Ly-1 antibody reactive in different cancer types

L Chen, C Jin, H Liu, R Feng, Z Li, J Zhang - Bioengineered, 2021 - Taylor & Francis
ABSTRACT LYAR (Ly-1 antibody reactive) is a transcription factor with a specific DNA-
binding domain, which plays a key role in the regulation of embryonic stem cell self-renewal …

Characterization of MAGEG2 with testis-specific expression in mice

J Jeong, S Jin, H Choi, JT Kwon, J Kim… - Asian Journal of …, 2017 - journals.lww.com
Male germ cell development is a well-defined process occurring in numerous seminiferous
tubules of the testis. Uncovering testicular novel genes related to intrinsic regulation of …

Lyar is a new ligand for retinal pigment epithelial phagocytosis

F Guo, Y Ding, NB Caberoy, G Alvarado… - Journal of cellular …, 2015 - Wiley Online Library
Phagocytosis is critical to tissue homeostasis, as highlighted by phagocytosis defect of
retinal pigment epithelial (RPE) cells with debris accumulation, photoreceptor degeneration …